BACKGROUND Bisphenol A (BPA), an environmental pollutant, can generate free radicals which damages the reproductive system. Vitamin C is an antioxidant which may prevent the adverse effects of free radicals. OBJECTIVE The aim was to investigate the effect of vitamin C on the ovary tissue in rats treated with BPA. MATERIALS AND METHODS In this experimental study, 24 female Wistar rats (200±2...

To investigate the early ovarian changes after cyclophosphamide treatment, immature rats primed for 48 h with pregnant mare serum gonadotropin were given injections i.p. of cyclophosphamide (100 mg/kg) at 1, 2, 4, 16, and 24 h before decapitation. Serum estradiol dropped significantly after 24 h of exposure to cyclophosphamide (P less than 0.001). Following 16 and 24 h of cyclophosphamide expos...

OBJECTIVE Polycystic ovary syndrome (PCOS) is associated with higher prevalence of cardiovascular risk factors but the relative prevalence of cardiovascular disease in women with PCOS has not previously been reported. We have compared cardiovascular mortality and morbidity in middle-aged women previously diagnosed with PCOS and age-matched control women. DESIGN A retrospective cohort study of...

The knowledge about ovarian reserve is essential to determine the reproductive potential and to improve the methods of fertility control for overpopulated species, such as white-tailed deer (Odocoileus virginianus). The goal of this study was to evaluate the effect of age on the female reproductive tract of white-tailed deer, focusing on ovarian features. Genital tracts from 8 prepubertal and 1...

CONTEXT The criteria for diagnosis of polycystic ovary syndrome (PCOS) have been modified and now include polycystic ovary morphology (PCOM). OBJECTIVE The purpose of this study was to determine the frequency of PCOS and PCOM in women with type 1 diabetes mellitus (DM1). DESIGN We evaluated the clinical, hormonal, and ultrasonographic characteristics in women with DM1 and compared them with...

background: polycystic ovary syndrome (pcos) is a heterogeneous complex genetic disorder characterized by hyperandrogenemia hyperinsulinemia insulin resistance and chronic anovulation. it is the most common endocrine disorder in women of reproductive age with an enigmatic pathophysiologic and molecular basis. obesity hyperandrogenism and infertility occur frequently in pcos which mostly have a ...

Objective PCOS is the most frequent female endocrine disorder, affecting 5%-10% of women, is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovaries. The aim of the present research is to evaluate the expression of steroidogenic acute regulatory protein (StAR) and CYP19 (aromatase) mRNA in the ovary of EV-induced PCOS rat model and the effect of the treadmill and running w...

Background: Ovarian tissue transplantation is now considered as a procedure to preserve the fertility of young woman patient undergoing cancer therapy. An essential strategy to improve the efficiency of ovarian transplantation is to overcome the initial ischemia reperfusion injury and free radicals production that lead to a significant follicular loss. The aim of this study was to investigate t...

Mot, Y., Reid, M.S. and Kofranek, A.M., 1980. Role of the ovary in carnation senescence. Scientia Hortic., 13: 377--383. Ovary growth in carnation flowers was inhibited by pre-treatments with silver thiosulfate which retarded petal senescence. Although the start of ovary growth preceded visible wilting of untreated flowers, the ovary does not appear to control carnation senescence. Its removal ...