The chronic fatigue syndrome is characterised by a fatigue that is disproportionate to the intensity of effort that is undertaken, has persisted for 6 months or longer, and has no obvious cause. Unless there has been a long period of patient- or physician-imposed inactivity, objective data may show little reduction in muscle strength or peak aerobic power, but the affected individual avoids hea...

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Traditionally, biomarkers have been of interest in sports in order to measure performance, progress in training and for identifying overtraining. During the last years, growing interest is set on biomarkers aiming at evaluating health-related aspects which can be modulated by regular physical activity and sport. The value or concentration of a biomarker depends on many factors, as the training ...

Regularization and Early Stopping are two of the most common techniques to deal with the overtraining problem in the Artificial Neural Networks field. The overtraining problem appears mostly in systems affected by noise in which after a certain amount of training, the neural network used for modelling starts to learn information specific from the training signal or the noise. It has already bee...

BACKGROUND Circulating free plasma DNA is implicated in conditions associated with tissue injury, including exercise-induced inflammation, and thus is a potential marker for athletic overtraining. METHODS We measured free plasma DNA along with C-reactive protein (CRP), creatine kinase (CK), and uric acid (UA) in 17 recreationally trained men participating in a 12-week resistance training regi...

BACKGROUND A psychocomportemental questionnaire has been devised by the consensus group of the Société Française de Médecine du Sport to characterise and quantify, using a list of functional and psychocomportemental signs, a state of "staleness", for which no biological indicator is unanimously recognised. OBJECTIVES To determine the relation between this diagnostic method and two hormones (c...

Despite a more than adequate protein intake in the general population, athletes have special needs and situations that bring it to the forefront. Overtraining is one example. Hard-training athletes are different from sedentary persons from the sub-cellular to whole-organism level. Moreover, competitive, "free-living" (less-monitored) athletes often encounter negative energy balance, sub-optimal...

A key challenge to optimising marathon running performance is to train with adequate frequency, duration and intensity as well as get enough recovery to optimise biological adaptations underlying performance. Some marathon runners train inadequately and underperform, while others perform poorly because they become injured or develop staleness in response to overtraining. Staleness, a depression...

The Overtraining Syndrome (OTS) is a physically debilitating medical condition that results in athletes being totally compromised in their capacity to perform and compete. Many physiological systems are affected by the process of overtraining and the development of the OTS which results from it; but one system in particular, the immune, is highly susceptible to degradation resulting in a reduct...

An experienced surgeant is able to make a prediction about the malignancy of an ovarium tumour by means of the presented medical information (such as medical images, morphology and demographic features). To support this classiication process, we try to automate the prediction by means of a supervised neural network. A neural network is able to deduce unknown relations from the data by means of ...