Seed storage proteins are synthesized as sources of carbon, nitrogen and sulfur for the next generation of plants. Reactive oxygen species serve as second messengers for signal transduction; however, molecular targets of oxidant signaling have not been defined. Here, many researchers showes that ligand–receptor mediated signaling promotes reactive oxygen species– dependent protein carbonylation...

Amyloid β-peptide (Aβ) is thought by many researchers to be central to the pathogenesis of Alzheimer’s disease (AD) (reviewed in Ref. 1). In addition, oxidative stress, manifested by protein oxidation and lipid peroxidation, is apparent in AD brain.2,3 Our laboratory developed a comprehensive hypothesis for neurotoxicity in AD brain that unites these two observations and provides a testable fra...