BACKGROUND Kindler Syndrome (KS) is an autosomal recessive skin disorder characterized by skin blistering, photosensitivity, premature aging, and propensity to skin cancer. In spite of the knowledge underlying cause of this disease involving mutations of FERMT1 (fermitin family member 1), and efforts to characterize genotype-phenotype correlations, the clinical variability of this genodermatosi...

medicinal plants are presumed to be natural sources of antioxidants that protect organisms from oxidative stresses. the present investigation aims to study the anti-oxidative stress activity of the stachys lavandulifolia (s. lavandulifolia) plant. this trial was conducted on 26 healthy human subjects. the study was done in a before after fashion. the included subjects were asked to consume the ...

Selenium supplementation could be effective on reproductive outcomes, biomarkers of inflammation, and oxidative stress among women with polycystic ovary syndrome (PCOS). The aim of the study was to determine the effects of selenium supplementation on reproductive outcomes, biomarkers of inflammation, and oxidative stress in PCOS patients. The present randomized double-blind, placebo-controlled ...

OBJECTIVE To investigate the oxidative damage to lung tissue and peripherial blood in PM2.5-treated rats. METHODS PM2.5 samples were collected using an auto-sampling instrument in summer and winter. Treated samples were endotracheally instilled into rats. Activity of reduced glutathione peroxidase (GSH-Px) and concentration of malondialdehyde (MDA) were used as oxidative damage biomarkers of ...

Individuals who move from one place to another in search of recyclable goods for financial benefits or other purposes are known as wastes pickers. This study aimed on assessment some toxico-inflammatory, hepato-renal and cardio-oxidative-stress biomarkers among pickers Ajegunle, Lagos State, Nigeria. Five milliliters blood specimens were withdrawn each the 120 participants into lithium heparin ...

Background: Patients with type 2 diabetes have increased levels of oxidative stress and inflammation. A high fruit and vegetable intake may be beneficial. Objective: To study whether fruit and vegetable intake and levels of plasma antioxidants relate to markers of oxidative stress and inflammation in a group of patients with type 2 diabetes. Further, to investigate whether plasma antioxidants a...

Polycystic ovarian syndrome (PCOS) is a condition that increases the risk of metabolic diseases, such as insulin resistance, diabetes mellitus, and obesity, among others. Oxidative stress state elevated oxidants reduced antioxidants, which can be detrimental to body. Reduced glutathione (GSH) an important material with antioxidant properties. This study aimed investigate status oxidative in PCO...

Glaucoma is a multifactorial neurodegenerative disease and the second leading cause of blindness. Detection clinically relevant biomarkers would aid better diagnoses monitoring during treatment. In glaucoma, protein composition aqueous humor (AH) for discovery biomarkers. This study analyzes AH concentrations putative in patients with primary open-angle glaucoma (POAG) compared to control group...

Title: CIRCULATING BIOMARKERS OF NITROOXIDATIVE STRESS IN YOUNG AND OLDER ACTIVE AND INACTIVE MEN Lori Beth Bjork, M.A., 2010 Directed By: Professor James M. Hagberg, PhD Department of Kinesiology Oxidative stress markers may be novel factors contributing to cardiovascular (CVD) risk. The purpose of this study was to examine the effects of long-term exercise, age, and their interaction on the p...

Phthalate has been used worldwide in various products for years. Little is known about the association between phthalate exposure and biomarkers of oxidative stress in adolescents and young adults. Among 886 subjects recruited from a population-based cohort during 2006 to 2008, 751 subjects (12-30 years) with complete phthalate metabolites and oxidation stress measurement were enrolled in this ...