We introduce photothermal optical lock-in Optical Coherence Microscopy (poli-OCM), a volumetric imaging technique, which combines the depth sectioning of OCM with the high sensitivity of photothermal microscopy while maintaining the fast acquisition speed inherent to OCM. We report on the detection of single 40 nm gold particles with a 0.5 μm lateral and 2 μm axial resolution over a 50 μm depth...

BACKGROUND The availability of haemodialysis machines equipped with on-line clearance monitoring (OCM) allows frequent assessment of dialysis efficiency and adequacy without the need for blood samples. Accurate estimation of the urea distribution volume 'V' is required for Kt/V calculated from OCM to be consistent with conventional blood sample-based methods. METHODS Ten stable HD patients we...

The rates of C H bond activation for various alkanes by [(N-N)Pt(Me)(TFEd(3))](+) (N N = Ar N C(Me) C(Me) N Ar; Ar = 3,5-di-tert-butylphenyl; TFE-d(3) = CF(3)CD(2)OD) were studied. Both linear and cyclic alkanes give the corresponding alkene-hydride cation [(N-N)Pt(H)(alkene)](+) via (i) rate determining alkane coordination to form a C H sigma complex, (ii) oxidative cleavage of the coordinated...

A series of 71 patients with multiple measured biopsies of the gastroesophageal junctional region permitting assessment of the presence and length of different glandular epithelial types is presented. All but nine of 53 patients in whom a 24-hour pH study was performed had abnormal reflux, suggesting that endoscopic recognition of an abnormal columnar mucosa at the gastroesophageal junction suf...

The dynamic behavior of fixed LV outflow tract stenosis partly resembles that of OCM. To analyze their differences we studied basal and postextrasystolic (post-PVC) peak-to-peak LV aortic gradients, aortic systolic pressure, and pulse pressure in 14 OCM and in 36 pure VAS without two-dimensional echocardiographic findings of OCM. Fifteen mild VAS had basal gradients similar to those of OCM (39 ...

Three-dimensional (3D) tissue imaging methods are expected to improve surgical management of cancer. In this study, we examined the feasibility of two 3D imaging technologies, optical coherence tomography (OCT) and optical coherence microscopy (OCM), to view human breast specimens based on intrinsic optical contrast. Specifically, we imaged 44 ex vivo breast specimens including 34 benign and 10...

This essay introduces contributions to a special issue exploring alternative accounts of organizational change management (OCM). It begins with identifying why such alternatives are needed by pointing to core assumptions within OCM, including a practical and ontological prochange bias, managerialism and universalism. The alternatives to OCM are then framed in terms of the constructionism associ...