Reactions of 0.5 eq. of the dinuclear complexes [(g-arene)Ru(l-Cl)Cl]2 (arene = g-C6H6, g-p-PrC6H4Me) and [(Cp*)M(l-Cl)Cl]2 (M = Rh, Ir; Cp* = g-C5Me5) with 4,6-disubstituted pyrazolyl-pyrimidine ligands (L) viz. 4,6-bis(pyrazolyl)pyrimidine (L1), 4,6-bis(3-methyl-pyrazolyl)pyrimidine (L2), 4,6-bis(3,5dimethyl-pyrazolyl)pyrimidine (L3) lead to the formation of the cationic mononuclear complexes...

Changes in the expression of the anti-apoptotic protein cFLIP (cellular FLICE inhibitory protein) were examined in the caprine corpus luteum (CL), during development and subsequent maintenance. Corpora lutea at four different stages were collected from Shiba goats, to measure the expression of cFLIP mRNA, protein and immunolocalization. Expression of short form cFLIP (cFLIPS) mRNA was highest a...

The poor patency rate following small-diameter vascular grafting remains a major hurdle for the widespread clinical application of artificial blood vessels to date. Our previous studies found that electrospun poly(L-lactide-co-epsilon-caprolactone) (P[LLA-CL]) nanofibers facilitated the attachment and growth of endothelial cells (EC), and heparin incorporated into P(LLA-CL) nanofibers was able ...

In the title complex, [AuCl(C24H20NOP)], the ligand has N, P and O electron-donating atoms but the Au(I) atom is coordinated only by the 'soft' P atom and an additional Cl atom in an almost linear fashion. Important geometrical parameters include Au-P = 2.2321 (13) Å, Au-Cl = 2.2820 (13) Å and P-Au-Cl = 176.49 (5)°. The furan ring is disordered over two positions in a 0.51 (2):0.49 (2) ratio.

PURPOSE To determine the distribution of invasive and cytotoxic genotypes among ocular isolates of P. aeruginosa and investigate the influence of the type III secretion system (T3SS) on adhesion to conventional, cosmetic, and silicone hydrogel contact lenses (CL). METHODS Clinical isolates from 2001 to 2010 were analyzed by multiplex PCR for exoS, exoU, and exoT genes. Bacterial adhesion to e...

Background: The SCN5A H558R polymorphism is potentially associated with several arrhythmias, including Brugada syndrome, atrial fibrillation, and sick sinus syndrome. Here we conducted a comprehensive meta-analysis to investigate the association between this polymorphism and arrhythmia risk. Methods and materials: Eligible studies extracted from the databases of PubMed, Web of Science, and Coch...

We determined expression and localization of the anti-apoptotic cellular FLICE inhibitory protein (cFLIP) in the porcine corpora lutea (CL) and corpus albicans (CA) during estrous and pregnancy. The CL and CA were collected at different stages of estrous to determine cFLIP immunolocalization, and mRNA and protein expression. The mRNA expression of the short cFLIP isoform (cFLIPS) was higher at ...

Reducing Stroke In-Hospital Mortality: Organized Care Is a Complex Intervention To the Editor: We read with great interest the article by Saposnik et al regarding the escalating levels of access to in-hospital care and stroke mortality.1 Many authors agree that the management of the patients in stroke care units has been the most substantial advance in stroke care; however, the mechanism by whi...