نتایج جستجو برای: p300
تعداد نتایج: 5950 فیلتر نتایج به سال:
Despite the P300-concealed information test's validity in detecting concealed memory when it is conducted immediately after the mock crime, whether the P300-CIT's detection efficiency is moderated by time delay remains unknown. Here, we conducted a mock crime study in which guilty participants were tested immediately after the mock crime or 1 month later. An innocent group was also tested. Assu...
The histone acetyltransferase (HAT) p300/CBP is a transcriptional coactivator implicated in many gene regulatory pathways and protein acetylation events. Although p300 inhibitors have been reported, a potent, selective, and readily available active-site-directed small molecule inhibitor is not yet known. Here we use a structure-based, in silico screening approach to identify a commercially avai...
Brain Computer Interfaces (BCI) are systems enabling humans to communicate with machines through signals generated by the brain. Several kinds of signals can be envisioned as well as means to measure them. In this paper we are particularly interested in even-related brain potentials (ERP) and especially visually-evoked potential signals (P300) measured with surface electroencephalograms (EEG). ...
OBJECTIVE To establish reference intervals for cognitive potential P300 latency using tone burst stimuli. METHODS This study involved 28 participants aged between 18 and 59 years. P300 recordings were performed using a two-channel device (Masbe, Contronic). Electrode placement was as follows: Fpz (ground electrode), Cz (active electrode), M1 and M2 (reference electrodes). Intensity correspond...
Cardiomyopathy is the main cause of death in Duchenne muscular dystrophy. Here, we show that oral administration of resveratrol, which leads to activation of an NAD(+)-dependent protein deacetylase SIRT1, suppresses cardiac hypertrophy and fibrosis and restores cardiac diastolic function in dystrophin-deficient mdx mice. The pro-hypertrophic co-activator p300 protein but not p300 mRNA was up-re...
The application of the P300 component of the event-related brain potential to the study of attentional impairment in schizophrenia is discussed, and two recent studies are described. In one, the relative effects on P300 of stimulus modality and probability were evaluated. The data showed that the P300 is smaller in schizophrenic patients relative to normal controls for low-probability auditory ...
The accessory Vpr protein of human immunodeficiency virus type 1 (HIV-1) is a promiscuous activator of viral and cellular promoters. We report that Vpr enhances expression of the glucocorticoid receptor-induced mouse mammary tumor virus (MMTV) promoter and of the Tat-induced HIV-1 long terminal repeat promoter by directly binding to p300/CBP coactivators. In contrast, Vpr does not bind to p/CAF...
We previously identified a set of transcription regulators, referred to as TIPs (tension-induced/inhibited proteins), with a role in myogenic versus adipogenic differentiation. Here we report that the TIP family comprises eight isoforms, all bearing a SANT (switching-defective protein 3, adaptor 2, nuclear receptor corepressor, and transcription factor IIIB) domain and some of them presenting S...
Evidence of hemispheric asymmetries in schizophrenia has been reported from different research areas. Asymmetries in evoked potential P300 topography are still controversial because of inconsistent findings. In the present study. previous results of abnormal lateralization of P300 were replicated in stabilized residual Schizophrenie patients. Auditory P300 was recorded during an odd ball task i...
سابقه و هدف: در روش های دروغ سنجی مغزی که در سال های اخیر به عنوان یک جایگزین برای سیستم های دروغ سنجی کلاسیک مطرح شده اند، کارتشخیص بین افراد راستگو و دروغگو با بررسی سیگنال های مغزی ثبت شده در طی آزمون خاص دروغ سنجی انجام می شود. این مقاله با هدف بالا بردن کارایی و ارائه روشی توانمند به منظور تشخیص فرد گناه کار در سیستم های دروغ سنجی با استفاده از سیگنال های مغزی ارائه شده است. مواد و روش ه...
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