We explore the use of proper priors for variance parameters of certain sparse Bayesian regression models. This leads to a connection between sparse Bayesian learning (SBL) models (Tipping, 2001) and the recently proposed Bayesian Lasso (Park and Casella, 2008). We outline simple modifications of existing algorithms to solve this new variant which essentially uses type-II maximum likelihood to f...

Many statistical machine learning techniques sacrifice convenient computational structures to gain estimation robustness and modeling flexibility. In this paper, we study this fundamental tradeoff through a SQRT-Lasso problem for sparse linear regression and sparse precision matrix estimation in high dimensions. We explain how novel optimization techniques help address these computational chall...

We consider regression problems where the number of predictors greatly exceeds the number of observations. We propose a method for variable selection that first estimates the regression function, yielding a “preconditioned” response variable. The primary method used for this initial regression is supervised principal components. Then we apply a standard procedure such as forward stepwise select...

We consider the problem of model selection and estimation in sparse high dimensional linear regression models with strongly correlated variables. First, we study the theoretical properties of the dual Lasso solution, and we show that joint consideration of the Lasso primal and its dual solutions are useful for selecting correlated active variables. Second, we argue that correlation among active...

The purpose of this article is to provide an adaptive estimator of the baseline function in the Cox model with high-dimensional covariates. We consider a two-step procedure : first, we estimate the regression parameter of the Cox model via a Lasso procedure based on the partial log-likelihood, secondly, we plug this Lasso estimator into a least-squares type criterion and then perform a model se...

It has been hypothesized that rare variants may hold the key to unraveling the genetic transmission mechanism of many common complex traits. Currently, there is a dearth of statistical methods that are powerful enough to detect association with rare haplotypes. One of the recently proposed methods is logistic Bayesian LASSO for case-control data. By penalizing the regression coefficients throug...

BACKGROUND In prognostic studies, the lasso technique is attractive since it improves the quality of predictions by shrinking regression coefficients, compared to predictions based on a model fitted via unpenalized maximum likelihood. Since some coefficients are set to zero, parsimony is achieved as well. It is unclear whether the performance of a model fitted using the lasso still shows some o...

Meinshausen and Buhlmann [Ann. Statist. 34 (2006) 1436–1462] showed that, for neighborhood selection in Gaussian graphical models, under a neighborhood stability condition, the LASSO is consistent, even when the number of variables is of greater order than the sample size. Zhao and Yu [(2006) J. Machine Learning Research 7 2541–2567] formalized the neighborhood stability condition in the contex...

We study the effective degrees of freedom of the lasso in the framework of Stein’s unbiased risk estimation (SURE). We show that the number of nonzero coefficients is an unbiased estimate for the degrees of freedom of the lasso—a conclusion that requires no special assumption on the predictors. In addition, the unbiased estimator is shown to be asymptotically consistent. With these results on h...

The Lasso estimate for linear regression parameters can be interpreted as a Bayesian posterior mode estimate when the priors on the regression parameters are independent double-exponential (Laplace) distributions. This posterior can also be accessed through a Gibbs sampler using conjugate normal priors for the regression parameters, with independent exponential hyperpriors on their variances. T...