Cocaine abuse occasionally causes extensive destruction of the osteocartilaginous structures of the nose, sinuses and palate, which mimics the clinical picture of other diseases associated with necrotising midfacial lesions. The differentiation of cocaine-induced midline destructive lesions (CIMDL) and limited granulomatosis with polyangiitis (GPA) may be difficult, particularly if patients do ...

OBJECTIVE The objective of this study was to improve and evaluate cleft lip/palate face models to give support information to the parents whose children have cleft lip/palate. MATERIAL AND METHOD Cleft lip/palate face models are made from a mold of about the same size as a child'head using rubber, wood and silicone and can be separated into parts to match the severity of the disease. The auth...

One of the most frequent congenital malformations is cleft lip and/or palate. The above-mentioned defect is a serious medical and social problem, and knowledge concerning its incidence pictures the scale of this phenomenon. the aim of the study was to determine the prevalence of cleft lip and/or palate in children in Łódź during the period between 2001 and 2010. Material and methods. We were ab...

We have identified a role for two evolutionarily related, secreted metalloproteases of the ADAMTS family, ADAMTS20 and ADAMTS9, in palatogenesis. Adamts20 mutations cause the mouse white-spotting mutant belted (bt), whereas Adamts9 is essential for survival beyond 7.5 days gestation (E7.5). Functional overlap of Adamts9 with Adamts20 was identified using Adamts9(+/-);bt/bt mice, which have a fu...

1014 The primary goal of palatoplasty is anatomical reconstruction of an intact palate to allow for development of normal speech while minimizing the incidence of oronasal fistula and ensuring long-term harmonious facial growth. Kriens1 first drew attention to the muscular anatomy of the soft palate, describing the abnormal positioning of the levator veli palatini muscle and loss of integrity o...

A thickened and abnormally long soft palate is mostly involved in the pathogenesis of both nasopharyngeal and oropharyngeal narrowing, affecting the respiratory activity in virtually all of the brachycephalic dogs suffering from Brachycephalic Airway Obstructive Syndrome (BAOS). The morphology of the soft palate in adult mesaticephalic and brachycephalic dogs has been previously described. In t...

IN the past, the sporadic, unpredictable occurrence of cleft palate made the study of its embryological origins difficult. The discovery by Fraser et al. (1954) that large doses of cortisone injected into pregnant strain A/ Jax females would cause cleft palate in 100 per cent, of the offspring, provided a means for studying cleft palate in all stages of its development. Also, the lower incidenc...

91 Tuberculosis of the oral cavity is often a consequence of active pulmonary tuberculosis. Tuberculosis of the oral cavity may occasionally result from a hematogenous spread of mycobacteria [1]. However, in the described patient, tuberculosis was not detected at any other body site. Although the larynx is commonly involved in upper respiratory tract tuberculosis, the anterior pillar of the fau...

INTRODUCTION This study aimed to investigate the mutation of T-box transcription factor TBX22 exon 5 in children with non-syndromic cleft palate. Four mutations in TBX22 exon 5 in X-linked cleft palate with ankyloglossia (CPX) patients had been identified in the previous studies. The study used the syndromic cleft palate susceptibility gene as a candidate gene for more common non-syndromic clef...

Electropalatography (EPG) is a well-known and established technique to measure the detailed time-varying contact pattern between the tongue and the hard palate. For EPG, the speaker wears an artificial palate in his mouth, which contains multiple electrodes (contact sensors) to register contact with the tongue. A related technique, albeit less known, is glossometry or optopalatography (OPG). Fo...