Lichen planus (LP) commonly involves the flexor aspects of the wrists, legs, and oral and genital mucous membranes. But it rarely occurs on the palms and/or soles. It mainly affects people in the age range 30~60 years. Childhood LP is reported to constitute only 1~4% of total cases of LP. In the literature, a few cases of LP on the palms and soles of pediatric patients have been reported. Here ...

these lesions improved and worsened cyclically along with buserelin acetate administration, the symptoms were relatively easily controlled with a topical steroid and no arthritis associated with SAPHO syndrome was apparent during all courses. Case 2 is that of a 34-year-old Japanese woman who presented with pustules on her palms and soles ( fig. 1 E). She noticed persistent palmar pustules and ...

The cornified cell envelope (CE) is a tough structure formed beneath the plasma membrane of terminally differentiated keratinocytes. Recent progress in understanding the molecular organization of the CE has disclosed the complex, yet orderly structure that functions as a protective barrier against the environment. We have recently demonstrated that two inherited skin diseases, Vohwinkel's syndr...

Infrared (IR) properties of k-(ET-C4)2Cu(CN)[N(CN)2] crystals in the normal (metallic) phase are reported. Deviations from conventional metallic properties are found and assigned to a strong electron correlation effect. # 2002 Elsevier Science B.V. All rights reserved.

Palmoplantar keratoderma (PPK) is a heterogeneous group of disorders. Epidermolytic PPK is a well delineated autosomal dominant entity, but no recessive form is known. Here we report two sons of phenotypically normal, consanguineous, Arab parents with features suggestive of PPK. They presented with patchy eczematous skin lesions followed by PPK and raised serum levels of IgE. Skin biopsy from t...

Clouston syndrome (hidrotic ectodermal dysplasia) is characterized by the clinical triad of nail dystrophy, alopecia and palmoplantar hyperkeratosis. Clouston syndrome is transmitted as an autosomal dominant trait and caused by mutations in the GJB6 gene (13q12), encoding the gap junction protein connexin 30 (C × 30). At present, there is no treatment for the disease and management is purely su...