materials and methods twelve natural compounds jaceosidin, withaferin a, curcumin, epigallocatechin-3-gallate (egcg), artemisinin, gingerol, ursolic acid, ferulic acid, berberin, silymarin, resveratrol, and indol-3-carbinol were docked against e6 and e7 oncoproteins of high-risk hpv types 16 and 18 using a protein-ligand docking software called autodock4.2. results out of these 12 natural compo...

BACKGROUND Seventy percent of sexually active individuals will be infected with Human Papillomavirus (HPV) during their lifetime. These infections are incriminated for almost all cervical cancers. In France, 3,068 new cases of cervical cancer and 1,067 deaths from cervical cancer occurred in 2005. Two vaccines against HPV infections are currently available and vaccination policies aim to decrea...

BACKGROUND The human papillomavirus (HPV) and its variants show wide geographical distribution and have been reported to cause cervical lesions. With cervical neoplasia as the leading cancer in Indian women, the aim of the present study was to evaluate the multiple infection HPV type distribution and variant genotypes in cervical samples from the coastal Karnataka region, India. MATERIALS AND...

background: the most common laryngeal mass in children is recurrent respiratory papillomatosis (rrp). studies have attempted to correlate viral typing and its aggressiveness. method: 29 patients with histologically confirmed rrp enrolled in adjuvant therapies. patients underwent several surgical interventions. results: hpv genotyping demonstrated 45% hpv-6 and 55% hpv-11. the mean age at the fi...

Overview The link between contraception and sexually transmitted infections (STIs), including HIV, constitutes a recurring theme and more emphasis is needed on the incorporation of the control of those infections in the provision of hormonal contraception through the promotion of dual method use. Confirmation of the vital role of infection with the human papillomavirus (HPV) in the aetiology of...

HPV (Human papillomavirus) affects 600,000 people worldwide each year. Almost all cervical cancers are associated with a past infection. In particular, the positivity to high-risk type HPV16 is detected in most of invasive cancers. FDA has approved prophylactic vaccines that protect against new infections, but do not induce immunity those patients established infections or neoplasms. To date, n...