The evolution of drug resistant Plasmodium parasites is a major challenge to effective malaria control. In theory, competitive interactions between sensitive parasites and resistant parasites within infections are a major determinant of the rate at which parasite evolution undermines drug efficacy. Competitive suppression of resistant parasites in untreated hosts slows the spread of resistance;...

Several parasites infest liver or biliary tree, either during their maturation stages or as adult worms. Bile iry tree parasites may cause pancreatitis, cholecystitis, biliary tree obstruction, recurrent cholangitis, biliary tree strictures and some may lead to cholangiocarcinoma. This review discusses the hepatobiliary parasites, and shows our experience in diagnosis and management of these pa...

Transgenic Leishmania parasites that encode the murine chemokine monocyte chemoattractant protein 1 (MCP-1) were generated. These parasites transcribed MCP-1 mRNA and secreted MCP-1 protein. Infection of BALB/c, C57BL/6, or MCP-1 knockout (KO) mice with these parasites resulted in minimal lesion development with fewer parasites in the infected foot, lymph node, and spleen compared to wild-type-...

Abstract. Sufardin, Sriwulan, Anshary H. 2022. Gyrodactylus (Monogenea: Gyrodactylidae) on marine ornamental fish Amphiprion percula from a aquaculture facility in Indonesia. Biodiversitas 23: 1023-1030. As popular (MOF), clownfishes are widely traded globally due to their beautiful appearance and relative ease of maintenance the aquarium. There is large amount literature biology ecology, but s...

Understanding drugs’ mechanism of action is integral to successful antimalarial drug development. Recent advances in chemoproteomic methods have created an avenue globally profile targets the Plasmodium parasites that cause malaria. Some these strategies even allow direct measurement living intracellular parasites. The cover feature highlights achievement probing drug–protein interactome intact...

For trophically transmitted parasites that manipulate the phenotype of their hosts, whether the parasites do or do not experience resource competition depends on such factors as the size of the parasites relative to their hosts, the intensity of infection, the extent to which parasites share the cost of defending against the host's immune system or manipulating their host, and the extent to whi...

Activation of complement by parasites (living parasites or purified parasite antigens) is involved in several mechanisms of the host parasite relationship. In most of the experiments performed in vitro, complement activation was found to be lethal for the parasites, but sometimes it could be essential for the development of parasitemia. Both classical and alternative complement pathways may be ...

Here, we test the hypothesis that virulent malaria parasites are less susceptible to drug treatment than less virulent parasites. If true, drug treatment might promote the evolution of more virulent parasites (defined here as those doing more harm to hosts). Drug-resistance mechanisms that protect parasites through interactions with drug molecules at the sub-cellular level are well known. Howev...

e-Diagnosis is a tool using electronic media (e-mail) amongst group of international experts in parasitology to collectively come up with diagnosis uncommon or difficult parasites. Why do we need e-Diagnosis? (1) Declining numbers the field especially morphologists; (2) Less importance/attention being given parasitic diseases humans developing world as it deemed be and unimportant, hence may mi...

during 1980-82, a total number of 4143 stool samples, from 2332 males and 1811 females, referred to the central laboratory of the school of public health, were examined for intestinal parasites. all the specimens were examined for intestinal parasites. all the specimens were examined by formol-ether concentration and wet-mount (ringer solution) techniques. the main prevalent pathogenic parasite...