For measurement of parathyroid hormone (PTH), the intact PTH (I-PTH) assay is generally used. However, I-PTH assay apparently detects PTH 7-84 fragments, in addition to PTH 1-84. The whole PTH (W-PTH) assay exhibits no cross-reactivity with PTH 7-84. Ratio of PTH 1-84 to non-(1-84) PTH has been proposed as a non-invasive indicator of bone turnover in patients with end-stage renal disease (ESRD)...

OBJECTIVES/HYPOTHESIS Compare parathyroidectomy patients based on age, including demographics, outcomes, and complications. STUDY DESIGN Retrospective review. METHODS Prospective parathyroidectomy database covering 1998 to 2007 was reviewed retrospectively. RESULTS A total of 687 patients underwent parathyroidectomy, including 247 (36%) >65 years old. Discharge was more often on day of su...

To determine (1) the relationship between primary hyperparathyroidism with mild hypercalcemia and psychiatric disturbances, bone density, or non-specific symptoms, and (2) the effect of parathyroidectomy on these outcomes, a systematic and critical review of the literature was conducted. Relevant citations were identified using MEDLINE (1966 to August, 1995) and PsycINFO (1967 to August, 1995)....

As more and more cases of primary hyperparathyroidism are being detected by screening for serum calcium concentration, the majority of patients are older individuals who are asymptomatic or have symptoms which are difficult to ascribe to hyperparathyroidism. Long-term follow-up has provided evidence that most asymptomatic patients who do not undergo parathyroidectomy will not develop symptomati...

Abstract Aim to measure the sensitivity of SPECT in localising parathyroid adenomas particularly whilst attempting minimally invasive parathyroidectomy. Method 2-cycles prospective study correlating and operative findings was conducted. All patients underwent ultrasound SPECT, those with concordant on both modalities parathyroidectomy, discordant had central neck exploration. Following findings...