Partial Least Squares (PLS) is an efficient multivariate statistical regression technique that has proven to be particularly useful for analysis of highly collinear data. To predict response variables Y from independent variables X, PLS attempts to find a set of common orthogonal latent variables by projecting both X and Y onto a new subspace respectively. As an increasing interest in multiway ...

Partial least squares (PLS) regression is a powerful and frequently applied technique in multivariate statistical process control when the process variables are highly correlated. Selection of the number of latent variables to build a representative model is an important issue. A metric frequently used by chemometricians for the determination of the number of latent variables is that of Wold’s ...

Signaling networks are made up of limited numbers of molecules and yet can code information that controls different cellular states through temporal patterns and a combination of signaling molecules. In this study, we used a data-driven modeling approach, the Laguerre filter with partial least square regression, to describe how temporal and combinatorial patterns of signaling molecules are deco...

Nicotine and a variety of other drugs and toxins are metabolized by cytochrome P450 (CYP) 2A6. The aim of the present study was to build a quantitative structure-activity relationship (QSAR) model to predict the activities of nicotine analogues on CYP2A6. Kernel partial least squares (K-PLS) regression was employed with the electro-topological descriptors to build the computational models. Both...

Recently, there has been an increased attention in the literature on the use of ensemble methods in multivariate regression and classification. These methods have been shown to have interesting properties both for regression and classification. In particular, they can improve the accuracy of unstable predictors. Ensemble methods have so far, been little studied in situations that are common for...

One important feature of the gene expression data is that the number of genes M far exceeds the number of samples N. Standard statistical methods do not work well when N < M . Development of new methodologies or modification of existing methodologies is needed for the analysis of the microarray data. In this paper, we propose a novel analysis procedure for classifying the gene expression data. ...

Panax ginseng C.A. Meyer is a herb used for medicinal purposes, and its discrimination according to cultivation age has been an important and practical issue. This study employed Fourier-transform infrared (FT-IR) spectroscopy with multivariate statistical analysis to obtain a prediction model for discriminating cultivation ages (5 and 6 years) and three different parts (rhizome, tap root, and ...

Intervention programs aimed at promoting study and work opportunities in the Information and Communications Technology (ICT) field to schoolgirls have been encouraged to combat a decline in the interest among girls to study ICT at school. The goal of our study is to investigate the influence of such interventions on schoolgirls’ intentions to choose a career in the ICT field by analysing compre...

Extracting facial feature points such as eyes, mouth and nose plays an important role in many applications. Most of the proposed methods are base on the geometrical features of images. In this paper, a novel method based on Partial Least Square Regression (PLSR) model is introduced to extract the relationship between the feature point coordinates and gray value distribution in the image. The pr...