نتایج جستجو برای: passive immunotherapy

تعداد نتایج: 102860  

Journal: :PLoS ONE 2009
Manisha Pandey Michael R. Batzloff Michael F. Good

Vaccination with J8-DT, a leading GAS vaccine candidate, results in protective immunity in mice. Analysis of immunologic correlates of protection indicated a role of J8-specific antibodies that were induced post-immunization. In the present study, several independent experimental approaches were employed to investigate the protective immunological mechanisms involved in J8-DT-mediated immunity....

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Oskar Adolfsson Maria Pihlgren Nicolas Toni Yvan Varisco Anna Lucia Buccarello Katia Antoniello Sophie Lohmann Kasia Piorkowska Valerie Gafner Jasvinder K Atwal Janice Maloney Mark Chen Alvin Gogineni Robby M Weimer Deborah L Mortensen Michel Friesenhahn Carole Ho Robert Paul Andrea Pfeifer Andreas Muhs Ryan J Watts

Passive immunization against β-amyloid (Aβ) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD). However, traditional passive immunization approaches carry the risk of Fcγ receptor-mediated overactivation of microglial cells, which may contribute to an inappropriate proinflammatory response leading to vasogenic edema and cerebral microhemorrhage...

Journal: :The International journal of developmental biology 2013
Vikram Virdi Ann Depicker

Passive immunization is a method to achieve immediate protection against infectious agents by administering pathogen-specific antibodies. It has proven to be lifesaving for many acute infections, and it is now also used for cancer treatment. Passive immunization therapies, however, are extremely expensive because they require large amounts of specific antibodies that are produced predominantly ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Brian H Kushner Kim Kramer Shakeel Modak Nai-Kong V Cheung

PURPOSE We used high-dose cyclophosphamide plus topotecan/vincristine (CTV) or irinotecan (C/I) in patients with resistant neuroblastoma. The aim was to use a regimen with little risk to major organs to (a) achieve or consolidate remission in heavily treated patients and to (b) induce an immunological state conducive to passive immunotherapy with the murine 3F8 antibody. EXPERIMENTAL DESIGN C...

Journal: :RUDN Journal of Medicine 2022

The sum of the effects all negative factors on human body is manifested, including in form an imbalance work immune system, which leads to a violation recognition and elimination foreign substances most diverse origin. This manifested increase frequency development inflammatory processes, risk their chronicity complications, identification opportunistic or conditionally pathogenic flora as path...

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