Unlike previous research on patient controlled analgesia, this study explores patient demand behavior over time. We apply clustering methods to disclose demand patterns among patients over the first 24h of analgesic medication after surgery. We consider demographic, biomedical, and surgery-related data in statistical analyses to determine predictors for patient demand behavior, and use stepwise...

T ueday, M arch 8, 2017 METHODS: Patients who underwent Exparel injection and On-Q implantation following autologous reconstruction were reviewed. Primary outcome measures included: Patient Controlled Analgesia (PCA) dose/frequency/ attempts/rejections, daily pain score, required oral postoperative pain medication, and return-to-ambulation. Postoperative oral pain medications were converted to ...

BACKGROUND Postoperative delirium is relatively common. However, the relationship between intravenous patient-controlled analgesia (IV-PCA) and delirium has not been thoroughly investigated. The aim of this study was to evaluate the effects of IV-PCA on the prognosis of postoperative delirium in patients undergoing orthopedic surgery. METHODS Medical records of 129 patients with postoperative...

BACKGROUND Every year, millions of patients receive sedatives for reduction of anxiety before surgery, but there is little objective data on the effect of this treatment on postoperative outcomes. To address this issue, the effects of benzodiazepine administration were evaluated in women undergoing abdominal surgery. METHODS Patients were randomized to receive 1 mg of oral lorazepam the night...

  Background: Our institution’s traditional pain management strategy after shoulder arthroplasty has involved the utilization of postoperative patient-controlled narcotic analgesia. More recently, we have implemented a protocol (TLC) that utilizes a multimodal approach. The purpose of this study was to determine whether this change has improved pain control and decreased narcotic utilization. ...

This study was designed to evaluate whether the nurses' assessment of postoperative pain can be an alternative to patients' self-reporting. We examined 187 patients receiving postoperative intravenous patient-controlled analgesia. The nurses assessed the patients' pain with three pain indices (therapeutic efficacy, pain intensity, and facial pain expression) 8 hr after operation. The patients r...

Benefits of microprocessor-controlled prosthetic knees (MPKs), such as significant reductions in falls and other important safety-related parameters, function, and mobility, have been well established in community ambulators (Medicare Functional Classification Level [MFCL]-3) with a transfemoral amputation (TFA). Little is known whether lowerfunctioning individuals (MFCL-2) with a TFA, who make...

Organohalide-respiring microorganisms can use a variety of persistent pollutants, including trichloroethene (TCE), as terminal electron acceptors. The final two-electron transfer step in organohalide respiration is catalyzed by reductive dehalogenases. Here we report the x-ray crystal structure of PceA, an archetypal dehalogenase from Sulfurospirillum multivorans, as well as structures of PceA ...

OBJECTIVES To elucidate the dynamics of analgesic consumption regarding intravenous patient controlled analgesia (IVPCA) during postoperative period is rather complex partly due to between-patient variation and partly due to within-patient variation. A statistical method was proposed to classify serial analgesic consumption into different classifications that were further taken as the multiple ...