OBJECTIVE We assessed the analgesic effect and feasibility of low-dose ketamine combined with a reduced dose of hydromorphone for emergency department (ED) patients with severe pain. METHODS This was a prospective observational study of adult patients with severe pain at an urban public hospital. We administered 0.5 mg of intravenous (IV) hydromorphone and 15 mg of IV ketamine, followed by op...

in order to avoid using cytotoxic drugs and to minimize prednisolone side effects in frequent relapsing or steroid-dependent idiopathic nephrotic syndrome, 35 patients, 3 to 15 (mean= 8.1) years of age, were studied. while in remission for at least 6 weeks, the dose of prednisolone was reduced to 0.1-0.37 (mean= 0.23) mg/kg/day as a single dose for 12 to 72 (mean= 27.6) months. it was followed ...

Myelosuppression continues to represent the major dose-limiting toxicity of cancer chemotherapy. Neutropenia and its complications, including febrile neutropenia, occur most often early in the course of treatment but are often underreported in clinical trials. In addition to associated morbidity, mortality, and cost, myelosuppression is often associated with reduced chemotherapy dose intensity....

Introduction: Nowadays, nuclear medicine (NM) imaging indications in medical practice is raising. A practical step to get closer to the optimization rule is collecting data about patients’ exposure and definition of guidance levels. The aim of this study was definition of local reference level in Isfahan city. Materials and Methods: Questionnaires were given...

Introduction:   Nowadays we are witnessing an exponential application of interventional radiology techniques in various communities as well as Iran. Radiological technique is regarded as  the  2nd  contributing  factor in  increasing  the  amount  of  public  doses  in various societies. So that related radiation protection organization has recommended measuring patient d...

Introduction: In 2000, the UNSCEAR reported that CT constitutes 5% of all the medical x-ray  examinations and it contributes 34% of the resultant collective dose worldwide. Children are more  sensitive to the ionizing radiations than adults. So, routine quality control tests are expected to be  carried out periodically on the CT scanners. The aim of this research was to estimate the effective  ...

Introduction: Assessment of occupational exposure to external radiation and the analysis of associated trends are imperative to observe changes that have taken place over time due to regulatory operations or technological advancements. Herein, we describe the occupational radiation exposure to workers employed in Nuclear Medicine (NM), Radiotherapy (RT), and Diagnostic Radiology (DR) department...

Background: Radiation absorbed dose to the red bone marrow, a critical organ in the therapy of thyroid carcinoma, is generally kept below 2 Gy for non-myeloablative therapies. The aim of this study was to calculate bone marrow radiation dose by using MIRDOSE3 package program and to optimize the safe limit of activity to be administered to the thyroid cancer patients. Materials and Methods: In t...

Background: The use of high-dose steroid therapy peri portoenterostomy may have a positive impact on the frequency of cholangitis and survival rate. Methods: A prospective study was conducted on two groups of patients (less than three months of age) suffering from biliary atresia from 1999 to 2005. The patients in group I (G I) were managed peri-operatively by high-dose methylprednisolone while...

this trial was performed to determine if a continuous low-dose infusion of methylprednisolone is as effective as its bolus of high-dose in reducing inflammatory response. the study was single-center, double-blinded randomized clinical trial and performed in a surgical intensive care unit of an academic hospital. in this study, 72 consecutive patients undergoing elective coronary artery bypass g...