Background: Immune thrombocytopenic purpura (ITP) is a disease characterized by decrease of the peripheral blood platelet count. The disease presents in acute and chronic forms. Because of the importance and high prevalence of ITP, it was decided to study the therapeutic response of patients with ITP. Material and Methods: A cross-sectional study was conducted at Ghaem hospital, Mashhad, Ira...

Background: Oral Aprepitant, a neurokinin-1 receptor antagonist, is suggested in combination with other antiemetic agents in preventing chemotherapy-induced nausea and vomiting(CINV) associated with emetogenic chemotherapeutic regimens in adolescents, but its efficacy and safety in pediatric patients more than six months are unknown. in this study, we used abitant drug (a generic name of Aprepi...

Objective The mortality of patients with locally advanced triple-negative breast cancer (TNBC) is high, and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is associated with improved prognosis. This retrospective study was designed and powered to investigate the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict pat...

Serum alpha-tocopherol of98(62 male and 36 female) cancer patients and 30 (13 male and 17 female) control healthy subjects was investigated. The cancer patients showed a significantly low level of alpha-tocopherol as compared to control healthy subjects. Also, significantly higher levels of serum alpha-tocopherol were found in complete remission patients as compared to the partial response...

introduction: the aim of this study is to assess the therapeutic efficacy and safety of a particular brand of ifn alpha (pdferon b®) in combination with ribavirin (rlba) on iranian patients with chronic hepatitis c (chc). the addition of riba to the standard treatment with interferon (ifn) alpha led to an improvement in sustained virologic response (svr) from less than 20% with ifn monotherapy ...

background: osteosarcoma is the most common bone sarcoma, and the third most common malignancy in children and adolescents. before 1970, amputation was the sole treatment. eighty percent of patients died from metastatic diseases, most commonly in the lungs. over the past three decades, effective neoadjuvant (preoperative) and adjuvant (postoperative) chemotherapy protocols have improved the abi...

introduction: management of early relapsed or refractory lymphoma [hodgkin & non- hodgkin lymphoma (hl & nhl)] is a matter of problem, especially when hematopietic stem cell support is not available. the aim of this study was to evaluate effectiveness of iev regimen ( ifosfamide, epirubicin, vp16), in lymphoma patients who are not candidate for stem cell transplantation. because the majority of...