Model-based performance predictions and reconfigurations enable optimizing resource efficiency while ensuring that Quality-of-Service demands are met in today’s complex ITsystems. The Descartes Modeling Language (DML) and the Palladio Component Model (PCM) are two architectural performance modeling formalisms applied in this context. This paper compares DML to PCM concerning similarities, diffe...

Phase change material (PCM), placed in an exterior wall, alters the temperature profile within the wall and thus influences the heat transport through the wall. This may reduce the net energy transport through the wall via interactions with diurnal temperature swings in the external environment or reduce the electricity needed to meet the net load through the wall by shifting the time of the pe...

Paracoccidioidomycosis (PCM) is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis and is endemic to Brazil. The aim of this study was to perform a retrospective analysis of the PCM cases in the countryside south of Rio Grande do Sul, Brazil. The files from four histopathology laboratories located in the city of Pelotas were obtained, and all of the epidemiological and clinic...

Human ES cells (hESCs) and human induced pluripotent stem cells (hiPSCs) are usually generated and maintained on living feeder cells like mouse embryonic fibroblasts or on a cell-free substrate like Matrigel. For clinical applications, a quality-controlled, xenobiotic-free culture system is required to minimize risks from contaminating animal-derived pathogens and immunogens. We previously repo...

Judea Pearl’s Causal Model is a rich framework that provides deep insight into the nature of causal relations. As yet, however, the Pearl Causal Model (PCM) has had a lesser impact on economics or econometrics than on other disciplines. This may be due in part to the fact that the PCM is not as well suited to analyzing structures that exhibit features of central interest to economists and econo...

The nanomechanical properties of individual cartilage cells (chondrocytes) and their aggrecan and collagen-rich pericellular matrix (PCM) were measured via atomic force microscope nanoindentation using probe tips of two length scales (nanosized and micron-sized). The properties of cells freshly isolated from cartilage tissue (devoid of PCM) were compared to cells that were cultured for selected...

BACKGROUND With preliminary data suggesting an increasing trend in attention-deficit/hyperactivity disorder (ADHD) prevalence in Europe, the use of psychotropic medications in this population needs to be better understood, particularly among patients with ADHD and no co-morbid psychiatric disorder. METHODS Medical charts of patients aged 6-17 years with one or more ADHD diagnosis between Janu...

The learned helplessness (LH) paradigm is characterized by learning deficits resulting from inescapable events. The aims of the present study were to determine if protein-calorie malnutrition (PCM) alters learning deficits induced by LH and if the neurochemical changes induced by malnutrition alter the reactivity to treatment with GABA-ergic and serotonergic drugs during LH. Well-nourished (W) ...

INTRODUCTION Paracoccidioidomycosis (PCM) is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC) and compare their characteristics with patients without neurological involvement, to identify unique...

The learned helplessness (LH) paradigm is characterized by learning deficits resulting from inescapable events. The aims of the present study were to determine if protein-calorie malnutrition (PCM) alters learning deficits induced by LH and if the neurochemical changes induced by malnutrition alter the reactivity to treatment with GABA-ergic and serotonergic drugs during LH. Well-nourished (W) ...