INTRODUCTION One of the top research priorities in acute kidney injury is related to the timing of renal replacement therapy (RRT) initiation. The purpose was to develop an index that might serve as a standardized concept of timing of initiation of RRT. METHODS A previously described database was used. We applied a multivariable Cox regression model with backward selection to characterize par...

INTRODUCTION Outcome studies in patients with acute kidney injury (AKI) have focused on differences between modalities of renal replacement therapy (RRT). The outcome of conservative treatment, however, has never been compared with RRT. METHODS Nine Belgian intensive care units (ICUs) included all adult patients consecutively admitted with serum creatinine >2 mg/dl. Included treatment options...

Background: Avian infectious bronchitis (IB) is a highly contagious viral disease which affects the poultry industry. The virus exists in a wide variety of genotypes, and phylogenetic analysis has been used to classify infectious bronchitis virus (IBV) strains. Aims: The object of the study is a molecular characterization of circulating IBV in Afghanistan as a ...

BACKGROUND Fabry disease, an X-linked lysosomal storage disorder caused by deficiency of alpha-galactosidase activity, is associated with progressive loss of kidney function. This study was undertaken to characterize Fabry disease among patients who reached end-stage renal disease. METHODS Data from 2,712 patients in the Fabry Registry were analysed to identify clinical characteristics of pat...

INTRODUCTION Positive fluid balance has been associated with an increased risk for mortality in critically ill patients with acute kidney injury with or without renal replacement therapy (RRT). Data on fluid accumulation prior to RRT initiation and mortality are limited. We aimed to study the association between fluid accumulation at RRT initiation and 90-day mortality. METHODS We conducted a...

BACKGROUND The optimal time to initiate renal replacement therapy (RRT) in intensive care unit (ICU) patients with acute kidney injury (AKI) is unclear. We examined the impact of early RRT on long-term mortality, risk of chronic kidney disease (CKD), and end-stage renal disease (ESRD). METHODS This cohort study included all adult patients treated with continuous RRT in the ICU at Aarhus Unive...

objective: the present study was undertaken to evaluate anti-depressant activity of myristica fragrans(ms). materials and methods: male wistar rats were subjected to imipramine and herbal extract ofms for their antidepressant activity using forced swimming test (fst), reserpine reversal test (rrt), haloperidol-induced catalepsy (hic), and pentobarbitone sleeping time (pst). results: administrat...

INTRODUCTION Patients with severe acute kidney injury (AKI) who are hospitalized at centers that do not provide renal replacement therapy (RRT) are frequently subjected to inter-hospital transfer for the provision of RRT. It is unclear whether such transfers are associated with worse patient outcomes as compared with the receipt of initial care in a center that provides RRT. This study examined...

Path planning plays an important role in autonomous robot systems. Effective understanding of the surrounding environment and efficient generation optimal collision-free path are both critical parts for solving path-planning problems. Although conventional sampling-based algorithms, such as rapidly exploring random tree (RRT) its improved version (RRT*), have been widely used problems because t...

Dynamic environments have obstacles that unpredictably appear, disappear, or move. We present the first sampling-based motion planning algorithm for real-time navigation through dynamic environments. Our algorithm, RRT, refines and repairs the same search-graph over the entire duration of navigation, i.e., despite changing obstacles and/or robot location. Whenever such changes are observed, e.g...