INTRODUCTION Patients with severe acute kidney injury (AKI) who are hospitalized at centers that do not provide renal replacement therapy (RRT) are frequently subjected to inter-hospital transfer for the provision of RRT. It is unclear whether such transfers are associated with worse patient outcomes as compared with the receipt of initial care in a center that provides RRT. This study examined...

Path planning is an important aspect and component in the research of mobile-robot-related technologies. Many path algorithms are only applicable to static environments, while practical tasks, uncertainty dynamic environments increases difficulty obstacle avoidance compared with environments. To address this problem, paper proposes RRT*-FDWA algorithm. RRT* first generates a global optimal path...

Dynamic environments have obstacles that unpredictably appear, disappear, or move. We present the first sampling-based motion planning algorithm for real-time navigation through dynamic environments. Our algorithm, RRT, refines and repairs the same search-graph over the entire duration of navigation, i.e., despite changing obstacles and/or robot location. Whenever such changes are observed, e.g...

INTRODUCTION Acute kidney injury (AKI) increases mortality and morbidity of critically ill patients. Mortality of patients treated with renal replacement therapy (RRT) is high. We aimed to evaluate the nationwide incidence of RRT-treated AKI in Finland, hospital and six-month mortality, and health-related quality of life (HRQoL) of these patients. METHODS We performed a retrospective cohort s...

In this paper we propose a new family of RRT based algorithms, named RRT+, that are able to find faster solutions in high-dimensional configuration spaces compared to other existing RRT variants by finding paths in lower dimensional subspaces of the configuration space. The method can be easily applied to complex hyperredundant systems and can be adapted by other RRT based planners. We introduc...

In order to assess the dynamics of influenza virus infection in pigs, serological and virological follow-ups were conducted in two whole batches of pigs from two different farms (F1 and F2), from 3 weeks of age until market age. Anti-swine influenza virus (SIV) antibodies (measured by ELISA and hemagglutination inhibition) and nasal virus shedding (measured by RRT-PCR and isolation in embryonat...

Among the different hemagglutinin (HA) subtypes of avian influenza (AI) viruses, H5, H7, and H9 are of major interest because of the serious consequences for the poultry industry and the increasing frequency of direct transmission of these viruses to humans. The availability of new tools to rapidly detect and subtype the influenza viruses can enable the immediate application of measures to prev...

Recognition of infections with human metapneumovirus (HMPV) among institutionalised elderly is rising. When HMPV was found to be the causative agent of an outbreak of pneumonia in a residential care facility for elderly in the Netherlands, an elaborate outbreak investigation was set up, including active surveillance for new cases. From clinical cases, defined by fever (> 38°C) and symptoms of r...

BACKGROUND The ability of pigs to become infected with low pathogenic avian influenza (LPAI) viruses and then generate mammalian adaptable influenza A viruses is difficult to determine. Yet, it is an important link to understanding any relationship between LPAI virus ecology and possible epidemics among swine and/or humans. OBJECTIVES Assess susceptibility of pigs to LPAI viruses found within...

For in vivo studies of influenza dynamics where within-host measurements are fit with a mathematical model, infectivity assays (e.g. 50% tissue culture infectious dose; TCID50) are often used to estimate the infectious virion concentration over time. Less frequently, measurements of the total (infectious and non-infectious) viral particle concentration (obtained using real-time reverse transcri...