CHESS pulse can suppress the signal originating from aliphatic fat protons but cannot suppress the signal from olefinic fat protons, which is near the resonance frequency of water protons. Adipose tissue contains various fat species; aliphatic fat comprises about 90 % and olefinic fat about 10 % of adipose tissue. Thus, CHESS pulse cannot be used to suppress the signal from adipose tissue compl...

Hepatic steatosis is a core feature of the metabolic syndrome and type 2 diabetes and leads to hepatic insulin resistance. Malonyl-CoA, generated by acetyl-CoA carboxylases 1 and 2 (Acc1 and Acc2), is a key regulator of both mitochondrial fatty acid oxidation and fat synthesis. We used a diet-induced rat model of nonalcoholic fatty liver disease (NAFLD) and hepatic insulin resistance to explore...

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis characterized by periods of remission and relapse. Mean platelet volume (MPV) is an indicator of systemic inflammation. In the present study, we aimed to determine the association between mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR), platelet distribution width (PDW) and clinical measures of diseases activi...

BACKGROUND Currently, the studies on the relationship between type 2 diabetes and platelets indicators were carried out on a selective small sample population generally. Large sample studies in this area are rare, especially in Chinese population. In this study, we aimed to investigate the relationship between type 2 diabetes and the mean platelet volume (MPV), platelet count (PLT) and platelet...

BACKGROUND Ventricular arrhythmias (VAs) originating from the left ventricular summit is a challenge for radiofrequency catheter ablation (RFCA). The present study aimed to investigate the appropriate RFCA strategy for VAs originating from the left ventricular summit. METHODS Forty-five consecutive patients with VAs arising from the left ventricular summit were successfully ablated at our car...

The need for a quantitative method to assess atherosclerosis in vivo is well known. This study tested, in a familiar animal model of atherosclerosis, a combination of magnetic resonance imaging (MRI) and image processing. Six spontaneously hyperlipidemic (Watanabe) rabbits were examined with a knee coil in a 1.5-T clinical MRI scanner. Inflow angio (2DI) and proton density weighted (PDW) images...

BACKGROUND Vasospastic disorders are common worldwide. In daily practice, routine blood samples are used for several investigations. In this study we aimed to determine the possible correlations between lymphocyte count, platelet indices, and the severity of vasospastic disorders. MATERIAL AND METHODS Data of 102 patients admitted to our department with vasospastic disorder symptomatology were ...

High-fat diets are often associated with greater caloric intake and weight gain. Since satiety during fat intake is induced by fat in the intestine we investigated the efficiency of a lipid compound that retards fat digestion to regulate fat intake. We found this compound to reduce high-fat food intake, body weight and blood lipids in Sprague-Dawley rats, without causing steatorrhea. The absenc...

Objective: This study aims to determine whether platelet indices (PI) (platelet count, mean volume [MPV], and distribution width [PDW]) are an additional diagnostic tool for neonatal sepsis (NS). Materials Methods: observational cross-sectional was done between April 2020 2021 at the intensive care unit (NICU) of Lala Lajpat Rai Memorial Medical College Meerut, Uttar Pradesh, India. Neonates wi...