The inhibitory effect of neutering on mammary gland tumor development in dogs has been well described. However, we observed that the effect of neutering on tumor malignancy may be altered by aging. Therefore, we characterized mammary tumors in aged dogs by analyzing the expression of cellular senescence markers. Expressions of p16, p38, p21, and p27 antibodies, which are senescence-associated m...

SUBJECT: GENETIC ASSAY OF TUMOR TISSUE TO DETERMINE PROGNOSIS OF BREAST CANCER (OncotypeDX TM , MammaPrint®) POLICY NUMBER: 2.02.27 CATEGORY: Laboratory Test EFFECTIVE DATE: 04/21/05 REVISED DATE: 04/20/06, 08/16/07, 10/23/08, 10/29/09, 12/16/10, 11/17/11, 11/15/12, 2/20/14, 01/22/15, 02/18/16, 03/16/17 (DELETED DATE: 11/21/13-2/20/14) PAGE: 1 OF: 9 • If a product excludes coverage for a servic...

The neural mechanisms that take place during learning and adaptation can be directly probed with brain-machine interfaces (BMIs). We developed a BMI controlled paradigm that enabled us to enforce learning by introducing perturbations which changed the relationship between neural activity and the BMI's output. We introduced a uniform perturbation to the system, through a visuomotor rotation (VMR...

Possibility of Brain-Computer Interface in Neurorehabilitation Junichi Ushiba, M.D. Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University (Clin Neurol 2011;51:927)

Although most instances of object recognition during natural viewing occur in the presence of saccades, the neural correlates of objection recognition have almost exclusively been examined during fixation. Recent studies have indicated that there are post-saccadic modulations of neural activity immediately following eye movement landing; however, whether post-saccadic modulations affect relativ...

In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum BDNF levels in the NPSLE patient with irreversible organic brain change were consistently low, ind...

Copyright © 2017 The Korean Society of Radiology RE: Should We Use a Monopolar or Bipolar Mode for Performing No-Touch Radiofrequency Ablation of Liver Tumors? Clinical Practice Might have Already Resolved the Matter Once and for All Olivier Seror, MD, PhD 2, , Olivier Sutter, MD Department of Radiology, Jean Verdier Hospital, Paris-Seine-Saint-Denis Universitary Hospitals, Bondy 93140, France;...

Brain-machine interfaces (BMIs) should ideally show robust adaptation of the BMI across different tasks and daily activities. Most BMIs have used overpracticed tasks. Little is known about BMIs in dynamic environments. How are mechanically body-coupled BMIs integrated into ongoing rhythmic dynamics, for example, in locomotion? To examine this, we designed a novel BMI using neural discharge in t...

Two patients with subacute sclerosing panencephalitis (SSPE) are described because of the course of the disease, which is still thought to be unusual but might prove to be rather common. In both cases there was apparent recovery after about two years of illness. One of the patients had a relapse after eight years of remission and seems to have recovered also from this second period of illness, ...