The role of lysyl oxidase-like 1 and fibulin-5 in the development of atherosclerosis and pelvic organ prolapse on their study of the correlation between expression of lysyl oxidase-like 1 (LOX-1) and fibulin-5 (F5) in the cardinal ligament tissue and pelvic organ prolapse (POP). In their elegant work, they evaluated the levels of LOX-1 and F5 in connective tissue of the cardinal ligament in ord...

Abstract The introduction of the tensionfree vaginal tape in 1995 drastically changed landscape surgical procedures for stress urinary incontinence (SUI). Because uncomplicated technique many urologists and gynecologists embraced procedure with tripled number annual beginning this century. At same time polypropylene was used development pelvic organ prolapse (POP). Especially use POP has caused...

To evaluate the factors affecting post operative stress-related urinary incontinence (POSUI), as well as the treatment and prevention of POSUI. Four hundred and eighty-nine patients were retrospectively reviewed between February 1, 2007 and December 31, 2009 who were with grade 2 or greater uterine and/or vaginal vault prolapse without urinary incontinence. Patients merely with pelvic organ pro...

This study aimed to investigate the relationship between bladder trabeculation, urinary function, and the stage of pelvic organ prolapse (POP). The medical records of 104 patients with POP who underwent cystoscopies and urodynamic studies were reviewed retrospectively. Age, incidence of detrusor instability, stage and site of POP, and the parameters of urodynamic studies of patients with and wi...

This study was carried out in order to compare the effects in different surgeries using mesh in pelvic organ prolapse patients whose leading points were C. Thirty-nine patients were categorized into 3 groups: group A pelvic reconstruction with hysterectomy; group B hysterectomy prior to pelvic reconstruction; and group C pelvic reconstruction with uterus preserved. At first visit, POP-Q stage w...

OBJECTIVES To evaluate the anatomical and functional outcomes of laparoscopic sacrocolpopexy using an anterior and a posterior polyester mesh, for the cure of genital prolapse at one year or longer. STUDY DESIGN This is a consecutive 5 year prospective observational study in which 119 patients presented with at least a Stage 2 apical prolapse, with an anterior or a posterior vaginal wall prol...

Introduction: Growing studies explored the association of polymorphism in C0L1A1 Sp1-binding site with susceptibility to pelvic organ prolapse (POP), but the results have remained controversial and conflicting. To investigate the effect of COL1A1 Sp1-binding site polymorphism on POP, we performed a meta-analysis. Methods: We searched PubMed and HuGE for case-control studies concerning the assoc...

BACKGROUND Female pelvic organ prolapse is a common condition that often leads to surgical intervention to alleviate symptoms. The relationship between symptoms of prolapse and pelvic organ descent however, remains unclear. AIM To determine the correlation between the symptom of a vaginal lump and objective measures of female pelvic organ descent. METHODS Women seen at a tertiary urogynaeco...

Background: Assessment of sexual function in prolapse cases is important. Studies focusing on relationship between and pelvic organ (POP) are sparse. Aims Objectives: The aim the study was to evaluate women with symptomatic POP. Materials Methods: Women undergoing surgery for POP were interviewed. Results: Among 60 POP, 35% accepted that they used find ways avoid intercourse due their prolapsed...

BACKGROUND Pelvic Organ Prolapse (POP) is estimated to affect 41%-50% of women aged over 40. Findings from the multi-centre randomised controlled "Pelvic Organ Prolapse PhysiotherapY" (POPPY) trial showed that individualised pelvic floor muscle training (PFMT) was effective in reducing symptoms of prolapse, improved quality of life and showed clear potential to be cost-effective. However, provi...