SCF (Skp1-Cullin-F-box) ubiquitin ligases comprise several dozen modular enzymes that have diverse roles in biological regulation. SCF enzymes share a common catalytic core containing Cul1⋅Rbx1, which is directed toward different substrates by a variable substrate receptor (SR) module comprising 1 of 69 F-box proteins bound to Skp1. Despite the broad cellular impact of SCF enzymes, important qu...

The article presents the concept of building a low-energy programmable controller architecture developed in accord-ance with IEC 61131-3 standard. universality concerns freedom choice central unit and possibility easy replacement control algorithm. One three methods software development distribution is selected for proposed solution. As part work, prototype was prepared based on evaluation elem...

Input shaping is a method of reducing residual vibrations in computer-controlled machines. Shaped command profiles are generated by convolving a sequence of impulses, an input shaper, with the desired command signal. The shaped command profile will move the system without residual vibration. The performance of several types of input shapers is compared to the time-optimal flexible-body control ...

human presence and accordingly establishing suitable condition for social interactions are important factors in shaping urban spaces. caring to different aspects of improving environmental qualities especially perception aspect and ease of perception from the environment with legibility improvement is an element that was emphasized from the base of urban design. the role of time, commence of da...

In this lon gi tu di nal study, preg nant women in Japan and the United States reported on three cop ing strat e gies. Two are indi vid u ally phrased: per sonal influ ence over out comes and accep tance of out comes. The third, social assur ance, is grounded in rela tion ships, not ing that close oth ers can influ ence out comes. A Euro pean Amer i can sam ple rated accep tance high est as a s...

Cytokines play a critical role in shaping the host immune response to Leishmania infection and directing the development of protective and non-protective immunities during infection. Cytokines exert their biological activities through the activation and translocation of transcription factors into the nucleus whether they drive the expression of specific cytokine-responsive genes. Signal transdu...

In the era of economic globalization, cultural goods trade has assumed a vital role in overall bilateral trade. It has become an emerging and transformative force behind socio-cultural-economic development and an important source of inclusive growth. Once virtually unlocked, trade in cultural goods is now fast growing with world-wide market openings. Trade liberalisation in cultural goods thus ...