نتایج جستجو برای: peripheral mononuclear cell pbmc

تعداد نتایج: 1813954  

Journal: :Memorias do Instituto Oswaldo Cruz 2000
B J Holaday

This study examined the role and source of endogenous interleukin-10 (IL) secretion in visceral leishmaniasis (VL). The amounts of endogenous and Leishmania specific IL-10 and interferon-gamma (IFN) secreted by peripheral blood mononuclear cells (PBMC) from VL patients were compared. The correlation coefficient between endogenous IL-10 secretion and Leishmania specific IFN-gamma was -0. 77, sug...

Journal: :Archives of disease in childhood 2000
T Yoshikawa M Ihira K Suzuki S Suga T Matsubara S Furukawa Y Asano

METHODS A total of 43 children with neurological signs and symptoms were enrolled in the study. All children were suspected of having meningitis, and lumbar punctures were performed. Human herpesvirus 6 (HHV-6) and HHV-7 DNA was detected in cerebrospinal fluid (CSF) and peripheral blood mononuclear cells (PBMC) by nested polymerase chain reaction. RESULTS Most patients had detectable serum an...

Journal: :Journal of clinical microbiology 1992
J P Vendrell A M Conge M Segondy S Lombroso M F Huguet A Bertrand F Janbon A Serre

We developed an assay to detect antibodies spontaneously secreted in vitro by peripheral blood mononuclear cells (PBMC) against Brucella spp. High levels of anti-Brucella immunoglobulin G (IgG) and/or IgM and/or IgA antibodies were detected in the cell supernatant solution of PBMC cultures for 12 patients suffering from acute or focalized brucellosis and for 5 patients recently vaccinated again...

2010
Eunice W. Nduati Dorothy H. L. Ng Francis M. Ndungu Peter Gardner Britta C. Urban Jean Langhorne

B cell and plasma cell responses take place in lymphoid organs, but because of the inaccessibility of these organs, analyses of human responses are largely performed using peripheral blood mononuclear cells (PBMC). To determine whether PBMC are a useful source of memory B cells and plasma cells in malaria, and whether they reflect Plasmodium-specific B cell responses in spleen or bone marrow, w...

Journal: :Molecular human reproduction 1998
J Jeremias S Mockel S S Witkin

The influence of semen on immunity in sexually active women has been scarcely studied. The effect of human semen on production of messenger RNA (mRNA) for the anti-inflammatory TH2-related cytokine, interleukin-10 (IL-10), the 70 kDa heat shock protein (HSP70) and the pro-inflammatory TH1-related cytokine, interferon-gamma (IFN-gamma) was examined. Co-incubation of peripheral blood mononuclear ...

Journal: :Clinical and diagnostic laboratory immunology 2003
Toshinobu Kuroishi Ken-ichi Komine Ken-ichi Asai Jin Kobayashi Kouichi Watanabe Takahiro Yamaguchi Shin-ichi Kamata Katsuo Kumagai

To elucidate the pathological roles of staphylococcal enterotoxin C (SEC) in bovine staphylococcal mastitis, a histopathological analysis of SEC-inoculated mammary glands was performed. SEC-inoculated mammary glands exhibited interstitial inflammation, and the leukocytes that migrated into the gland were predominantly polymorphonuclear neutrophils (PMN). In the gland cistern tissues dissected f...

Journal: :The Journal of infectious diseases 2001
H Imamichi K A Crandall V Natarajan M K Jiang R L Dewar S Berg A Gaddam M Bosche J A Metcalf R T Davey H C Lane

In an effort to identify the sources of the viruses that emerge after discontinuation of therapy, analyses of human immunodeficiency virus (HIV) quasi species were done for 3 patients with sustained levels of HIV RNA of <50 copies/mL for 1-3 years. The sequences found in the rebounding plasma virus were closely related to those of the actively replicating form of viruses present before the init...

2011
Young Joo Shin Joon Young Hyon Seonhowa Kim Jae Woong Koh Soon Il Kwon Won Ryang Wee

PURPOSE To investigate the effect of cysteamine (CYS) on mixed peripheral blood mononuclear cells (PBMCs)--human corneal endothelial cell (HCEC) reaction (MLER). METHODS PBMC stimulation assay was performed using cultured HCEC. MLERs were treated with various concentrations of CYS (0-20 mM). The proliferation rate and secretion profiles of transforming growth factor-β1 (TGF-β1) and interleuki...

2012
Johanna M. Gostner Sebastian Schröcksnadel Kathrin Becker Marcel Jenny Harald Schennach Florian Überall Dietmar Fuchs

Antimalarial chloroquine is also used for the treatment of immune-mediated diseases. The interference of chloroquine with interferon-γ-induced tryptophan breakdown and neopterin production has been investigated in human peripheral blood mononuclear cells (PBMC) in vitro. Micromolar concentrations (2-50 μM) of chloroquine dose-dependently suppressed mitogen-induced tryptophan breakdown in PBMC b...

2014
M. L. Martinez-Fierro I. Garza-Veloz K. Carrillo-Sanchez V. Martinez-Gaytan R. Cortes-Flores M. A. Ochoa-Torres G. G. Guerrero I. P. Rodriguez-Sanchez C. O. Cancela-Murrieta M. Zamudio-Osuna J. I. Badillo-Almaraz C. Castruita-De la Rosa

OBJECTIVE To evaluate the peripheral blood mononuclear cell (PBMC) expression levels of hemeoxygenase 1 (HMOX-1), superoxide dismutase 1 (SOD-1), vascular endothelial growth factor A (VEGF-A), transforming growth factor beta 1 (TGF-β1), interleukin (IL)-6, IL-15 and AdipoQ genes to study their association with preeclampsia (PE). METHODS A total of 177 pregnant women were recruited: 108 cases ...

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