141 In-Vitro Contractions of Pregnant Rat Myometrium Pretreated with Oxytocin: Comparison of Various Combinations of Uterotonic Agents Abstract Type: Original Research Mrinalini Balki, M.B., B.S., M.D.; Magda Erik-Soussi, M.Sc.; John Kingdom, M.D.; Jose CA Carvalho, M.D., Ph.D. Mount Sinai Hospital, University of TorontoType: Original Research Mrinalini Balki, M.B., B.S., M.D.; Magda Erik-Souss...

INTRODUCTION Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition. We investigated the effect of OA supplementation on PG production using an in vitro model of ovine placenta. METHODS Maternal endometrium (ME) and fetal allantochorion (FC) were collected in...

Prehypertension is a risk factor for atherosclerosis. We investigated alterations in plasma metabolites that are associated with prehypertension. A group of 53 individuals was identified who remained within the range of prehypertension during repeated measurements in a 3-year period. This group was compared with the control group of 53 normotensive subjects who were matched for age and gender. ...

Twenty-four postpartum Sahiwal cows that did not show oestrus upto 85 days postpartum were randomly divided into two equal groups, A and B. Group A cows were injected 2 ml Prostavet injection containing 5 mg Etiproston, a synthetic analogue of PGF2α (Virbac, France) intramuscularly at day 85 postpartum on chronological basis of calving dates without palpation. A second injection was given 11 da...

Penelitian ini bertujuan membuat pemodelan untuk diagnosis repeat breeding (RB) pada sapi aceh berdasarkan intensitas estrus, profil hormonal, biokimia darah, dan jumlah infeksi bakteri saluran uterus. Hewan yang digunakan penelitian adalah 16 ekor terdiri atas 7 fertil 9 RB, berumur 3-8 tahun dengan skor kondisi tubuh (BCS) 3-4. Seluruh RB dilakukan sinkronisasi estrus menggunakan hormon PGF2α...

LutaLyse® Injection (dinoprost injection) is the most-researched, most-recommended, and most-used prostaglandin that cattle producers and veterinarians have trusted for more than 35 years. Dinoprost, the active ingredient of LutaLyse, is the naturally occurring prostaglandin F2α (PGF2α) that can help producers control breeding, improve pregnancy rates, reduce reproductive culls, reduce time nec...

BACKGROUND Several studies suggest an increase of oxidative stress and a reduction of endothelial function in obstructive sleep apnoea syndrome (OSAS). We assessed the association between OSAS, endothelial dysfunction and oxidative stress. Further aim was to evaluate the effect of nasal continuous positive airway pressure (nCPAP) on oxidative stress and arterial dysfunction. METHODS We studie...

The inducible isoform of nitric oxide synthase (iNOS) is expressed after systemic administration of lipopolysaccharide (LPS). The importance of expression of iNOS in blood vessels is poorly defined. Because nitric oxide from iNOS may alter vasomotor function, we examined effects of LPS on vasomotor function in carotid arteries from iNOS-deficient mice. We studied contraction of the carotid arte...

The efficiency of a short-term treatment with an intravaginal device containing progesterone (CIDR) combined with pregnant mares’ serum gonadotrophin (PMSG) and prostaglandin analogue (PGF2α) was evaluated for the induction of estrus, initiation of cyclic activity, and fertility in postpartum suckled yak cows. Seventy-five postpartum suckled yak cows were assigned to three treatments: (1) inser...