More accurate prediction of the prognosis in women with node-negative breast cancer may improve physicians' ability to identify the patients most likely to benefit from systematic adjuvant therapy. With this in mind, we performed DNA flow-cytometric measurements of ploidy and the fraction of cells in the synthesis phase of the cell cycle (S-phase fraction) on 395 specimens of node-negative brea...

The stability of two-dimensional Poiseuille flow and plane Couette flow for concentrated suspensions is investigated. Linear stability analysis of the two-phase flow model for both flow geometries shows the existence of a convectively driven instability with increasing growth rates of the unstable modes as the particle volume fraction of the suspension increases. In addition it is shown that th...

The primary purpose of this study was to evaluate the prognostic significance of Ki-67, a cell proliferation-associated antigen, in a large group (n = 674) of axillary node-negative breast cancer cases with long-term follow-up and to correlate Ki-67 antigen expression with S-phase fraction. Ki-67 immunostaining was assessed both semiquantitatively and quantitatively. The statistical analysis fo...

In this paper, a modified two-fluid model has been adopted to simulate the process of upward vertical subcooled flow boiling of refrigerant R-113 in a vertical annular channel at low pressure. The modified model considers temperature dependent properties and saturation temperature variation and was validated against a number of published low-pressure subcooled boiling experiments. The results s...