Phenanthrene (PHE) is one of the model compounds polycyclic aromatic hydrocarbons (PAHs). In this study, a natural PHE-degrading microbial consortium, named HJ-SH, with very high degradation efficiency was isolated from soil exposed to long-term PHE contamination. The results GC analysis showed that consortium HJ-SH degraded 98% 100 mg/L in 3 days and 93% 1000 5 days, an higher than any other c...

A fragment condensation solution phase assembly of the naturally occurring CB(1) inverse agonist nonapeptides, Pro-Val-Asn-Phe-Lys-Phe/Leu-Leu-Ser-His-OH (hemopressins), and two other homologues: N-terminal 2-amino acid (dipeptide) extended undecapeptide, Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH, and three-amino acid (tripeptide) extended dodecapeptide, Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu...

Solubility and permeability of nitrofurantoin (NITRO) were compared with those its cocrystals containing isoniazid (ISO), bipyridyl (BIP), or phenanthroline (PHE) as coformers, their parent mixtures. NITRO dissolution profiles evaluated via HPLC; we resorted to molecular dynamics (MD) simulations rationalize the experimental data on basis nitrofurantoin–coformers nitrofurantoin–water intermolec...

Novel polyherbal formulation (PHE) containing mainly the ethanolic extract of Adhatoda vasica Nees. (leaf), Clerodendrum serratum Linn. (root), Curcuma longa Linn. (rhizome), Solanum xanthocarpum Schrad & Wendl. (fruit) and Piper longum Linn. (fruit). HPTLC analysis of the herbal extracts of PHE revealed presence of 0.25%w/w vasicine, 3.4%w/w piperine, 1.56%w/w curcumin and 0.04%w/w solasodine....

Acetylcholinesterase (AChE) is a significant component of the membrane contributing to the permeability changes during synaptic transmission and conduction. Phenylketonuria is a group of metabolic disorders in which phenylalanine (Phe) is highly elevated in blood (up to 0.1 M) resulting in mental retardation etc. AChE activity was measured spectrophotometrically after incubation with various Ph...