abstract objective febrile convulsions (fc) are the most common convulsive events in childhood, occurring in 2-5% of children. about one third of these children will have  a recurrence during a subsequent febrile infection. this sudden neurologic problem is extremely frightening and emotionally traumatic for parents so some physicians try to prevent recurrence of fc by prescribing different dru...

This study investigated alterations in the function and expression of P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) at the blood-brain barrier (BBB) of acute liver failure (ALF) mice and its clinical significance. ALF mice were developed using intraperitoneal injection of thioacetamide. P-GP, BCRP, and MRP2 functions were de...

objective in this study, we investigated the changes of the serum levels of thyroidhormones including thyroxine (t4), triiodothyronine (t3), t3 resin uptake andthyroid stimulating hormone (tsh) in epileptic children during treatment withanti-epileptic drugs (aeds) including carbamazepine (cbz), primidone (prm),phenobarbital and valproic acid (vpa). materials and methods this study consisted of ...

Abstract Cancer‐related fatigue (CRF) and stress are common symptoms in cancer patients represent early side effects of treatment which affect the life quality patients. CRF may partly depend on disruption circadian rhythm. Locomotor activity corticosterone rhythms two important outputs can be used to analyze possible function during development treatment. The present study analyzes relationshi...

Case presentation: The parents of a 38 months-old male patient seek neurological consultation for refractory seizures. He was previously treated with phenobarbital 4,7mg/kg/day and valproate 41mg/kg/day febrile seizures that started at 30 months. described generalized myoclonic following staring. presented every 2 to 3 weeks when it added clobazam 0,55mg/kg/day, oxcarbazepine 33,3mg/kg/day cann...