نتایج جستجو برای: phenylalanine ammonialyase

تعداد نتایج: 15360  

Journal: :iranian biomedical journal 0
morteza bagheri isa abdi rad nima hosseini jazani rasou zarrin ahad ghazavi

background: the variable numbers of tandem-repeat (vntr) alleles at the phenylalanine hydroxylase (pah) gene have been used in carrier detection and prenatal diagnosis in phenylketonuria families. this study was carried out to analyze vntr alleles at the pah gene in iranian azeri turkish population. methods: in this study, 200 alleles from general population were studied by pcr. results: the fr...

Journal: :iranian journal of biotechnology 2013
abolghasem abbasi kajani mohamma reza mofid khalil alami saeid

background: taxol is one of the most important anti-cancer drugs, which is obtained from yew trees (taxus sp.). t+he fist step in side chainassembly of taxol is catalyzed by phenylalanine aminomutase, which converts α-phenylalanine to β-phenylalanine.objectives: in this study, for the fist time, we report on the cloning, preliminary expression and characterization of a full-length gene andcdna ...

Journal: :The Journal of nutrition 2012
Kristine L Urschel Raymond J Geor Mark D Hanigan Pat A Harris

Stable isotope infusion methods have not been extensively used in horses to study protein metabolism. The objectives were to develop infusion and sampling methodologies for [1-(13)C] phenylalanine and apply these methods to determine whether the addition of supplemental amino acids to a control diet affected whole-body phenylalanine kinetics in mature horses. Arabian geldings were studied using...

Journal: :The Biochemical journal 1996
A P Døskeland A Martinez P M Knappskog T Flatmark

The phosphorylation of human phenylalanine hydroxylase by cyclic AMP-dependent protein kinase was studied using recombinant enzyme expressed as a fusion protein in the pMAL system of Escherichia coli. Using the target sequence of the restriction protease enterokinase (Asp4-Lys) as the linker peptide, 100% full-length human phenylalanine hydroxylase was obtained on protease cleavage. The fusion ...

Journal: :The Journal of biological chemistry 1972
E Shrawder M Martinez-Carrion

The transamination by pig mitochondrial and supernatant aspartate transaminase of aromatic amino acids was studied in order to determine if an analogy exists between these enzymes and a previously reported brain phenylalanine transaminase (GEORGE, H., AND GABAY, S. (1968) Biochim. Biophys. Ada, 167, 555). Supernatant and mitochondrial aspartate transaminase from pig heart can utilize aromatic a...

2017
Rianne Jahja Francjan J. van Spronsen Leo M. J. de Sonneville Jaap J. van der Meere Annet M. Bosch Carla E. M. Hollak M. Estela Rubio-Gozalbo Martijn C. G. J. Brouwers Floris C. Hofstede Maaike C. de Vries Mirian C. H. Janssen Ans T. van der Ploeg Janneke G. Langendonk Stephan C. J. Huijbregts

Cognitive and mental health problems in individuals with the inherited metabolic disorder phenylketonuria (PKU) have often been associated with metabolic control and its history. For the present study executive functioning (EF) was assessed in 21 PKU patients during childhood (T1, mean age 10.4 years, SD = 2.0) and again in adulthood (T2, mean age 25.8 years, SD = 2.3). At T2 additional assessm...

Journal: :iranian journal of public health 0
a haghighatnia s vallian j mowla z fazeli

background: genetic diversity of three polymorphic markers in the phenylalanine hydroxylase (pah) gene region including pvu ii (a), pahstr and msp i were investigated. methods: unrelated individuals (n=139) from the iranian populations were genotyped using primers specific to pah gene markers including pvu ii(a), msp i and pahstr. the amplified products for pvu ii(a), msp i were digested using ...

Journal: :Journal of the American Chemical Society 2017

Journal: :Reactome - a curated knowledgebase of biological pathways 2003

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