Dividing cultured cells contain much larger pools of the four dNTPs than resting cells. In both cases the sizes of the individual pools are only moderately different. The same applies to mitochondrial (mt) pools of cultured cells. Song et al. [Song S, Pursell ZF, Copeland WC, Longley MJ, Kunkel TA, Mathews CK (2005) Proc Natl Acad Sci USA 102:4990-4995] reported that mt pools of rat tissues ins...

Although urinary excretion levels of dialkyl­ phosphates (DAPs)—which are metabo­ lites and environmental degradates of OP insecticides—are useful as quantitative indi­ cators of exposure to OPs in agricultural workers, they are not as useful for the gen­ eral population. For agricultural workers, the source of the OP and time of exposure are typically known, and there is substan­ tial exposure...

Rhizosphere microorganisms are a heterogenous group of bacteria, including plant growth promoting bacteria, which can improve extent or quality of plant growth direct and indirect. Generally large array of bacteria, including species of Pseudomonas, Azospirillum, Azotobacter, Klebsiella, Enterobacter, Alcaligenes, Arthrobacter, Burkholderia, Bacillus and Serratia have been reported to enhance p...

PURPOSE To assess effects of elevated glucose levels on retinal glycolysis and sorbitol pathway metabolism. METHODS Freshly isolated retinas from normal male Sprague-Dawley rats were incubated for 2 hours at 37 degrees C, pH 7.45, in Krebs bicarbonate-Hepes buffer containing 5, 10, 20, or 30 mM glucose. Glycolytic metabolites, sorbitol, and fructose were measured in extracts of retina and med...

Worldwide pollution of soils, rivers, streams and lakes from anthropogenic activities has been one the most crucial environmental problems since beginning 20th century. In Santa, increasing use agrochemicals is disturbing, as farmers have little or no idea about application techniques effects these chemicals on environment. The objective this work was to determine knowledge pesticides fertilize...

Although urinary excretion levels of dialkyl­ phosphates (DAPs)—which are metabo­ lites and environmental degradates of OP insecticides—are useful as quantitative indi­ cators of exposure to OPs in agricultural workers, they are not as useful for the gen­ eral population. For agricultural workers, the source of the OP and time of exposure are typically known, and there is substan­ tial exposure...

The tumor suppressor p53 is a major transcription factor that induces genes regulating cell cycle arrest and death and which is inactivated in about half of all human cancers. Despite considerable research on p53, mechanisms regulating its activation have not been fully elucidated. We have recently established that the enzyme inositol polyphosphate multikinase (IPMK) is a transcriptional co-act...

In aqueous solution, the reducing sugar phosphates D-arabinose 5-phosphate, D-ribose 5-phosphate, D-fructose 1,6-bisphosphate, D-fructose 6-phosphate, D-glucose 6-phosphate and D-mannose 6-phosphate provide metal-binding sites at their glycose core on reaction with Pd(II)(en) or M(III)(tacn) residues (M = Ga, Co; en = ethylenediamine, tacn = 1,4,7-triazacyclononane). The individual species were...

[1] Water played a major role in the formation and alteration of rocks and soils in the Columbia Hills. The extent of alteration ranges from moderate to extensive. Five distinct rock compositional classes were identified; the order for degree of alteration is Watchtower ffi Clovis > Wishstone ffi Peace > Backstay. The rover’s wheels uncovered one unusual soil (Paso Robles) that is the most S-ri...

Metal oxides, in general, are known to exhibit significant wettability towards water molecules because of the high feasibility of synergetic hydrogen-bonding interactions possible at the solid-water interface. Here we show that the nano sized phosphates of rare earth materials (Rare Earth Phosphates, REPs), LaPO4 in particular, exhibit without any chemical modification, unique combination of in...