Postperfusion lung syndrome is rare but can be lethal. The underlying mechanism remains uncertain but triggering inflammatory cascades have become an accepted etiology. A better understanding of the pathophysiology and the roles of inflammatory mediators in the development of the syndrome is imperative in the determination of therapeutic options and promotion of patients' prognosis and survival...

Alzheimer's disease (AD) is characterised by macroscopic cerebral damages which can be studied in vivo with neuroimaging techniques, even at the earliest stage. Studies were conducted in patients with amnestic Mild Cognitive Impairment (MCI) who best represent incipient AD. Right temporo-parietal hypometabolism, assessed by resting-state (18)FDG-PET, distinguishes patients who further develop A...

.......................................................................................................xv Introduction...................................................................................................1 1.1 Scope of This Thesis................................................................................................2 1.2 Thesis Overview .......................................

Idiopathic organ transplant chorioretinopathy is a rare disease associated with kidney and heart transplantation. We present a case secondary to liver transplantation including its multimodal imaging, differential diagnosis, and physiopathology discussion.

Superoxide is known to affect vascular physiology in several ways and has also been recognized to contribute significantly to vascular physiopathology. Here we discuss the emerging role of superoxide as an essential signaling molecule in normal physiology.

INTRODUCTION There is a controversy concerning the terminology and definition of rhinitis in pregnancy. Gestational rhinitis is a relatively common condition, which has drawn increasing interest in recent years due to a possible association with maternal obstructive sleep apnea syndrome (OSAS) and unfavorable fetal outcomes. OBJECTIVE To review the current knowledge on gestational rhinitis, a...

Urinary tract obstruction is a frequent cause of renal impairment. The physiopathology of obstructive nephropathy has long been viewed as a mere mechanical problem. However, recent advances in cell and systems biology have disclosed a complex physiopathology involving a high number of molecular mediators of injury that lead to cellular processes of apoptotic cell death, cell injury leading to i...