Radial retroiridal pigmented lines found on the peripheral anterior capsule of the lens have been interpreted since their description by Vogt as remnants of the tunica vasculosa retroiridalis (membrana capsulopupillaris). They were found in nearly 5% of adults. A control examination of 1108 children and juveniles failed to reveal a single example. They are therefore thought to be caused by pigm...

Question A 73-year-old male, referred by his GP with dyspepsia unresponsive to proton pump inhibitors. His past medical history included COPD, ischemic heart disease, Iron deficiency anaemia (IDA) investigated with colonoscopy and a colonic polyp removed 2012. In the absence of a clear treatable condition behind his IDA, his low Iron was treated with Iron supplement Ferrous Sulphate. His curren...

Topica! tyrosine has been proposed as a tanning accelerator because tyrosine is a precursor of melanin. We tested formulations containing O, 1, and 2% L-tyrosine topically on 14 individuals daily for 28 days. Percutaneous absorption using "C tyrosine was 1.23% in 24 hr. No enhanced pigmentation was clinically evident in any of the subjects. In this study, we were unable to demonstrate that topi...

BACKGROUND/AIMS It is well known that light skin pigmentation is a risk factor for cutaneous melanoma. The aim of this study was to investigate the analogous association between choroidal pigmentation and posterior uveal melanoma. METHODS Cross sectional study of 65 consecutive patients diagnosed with posterior uveal melanoma (melanoma group) and 218 consecutive patients referred for general ...

Similar phenotypic changes have evolved independently in many animal taxa. It is unknown whether independent changes involve the same or different developmental and genetic mechanisms. Myriad pigment patterns in the genus Drosophila offer numerous opportunities to address this question. Previous studies identified regulatory and structural genes involved in the development and diversification o...

The Lc petunia system, which displays enhanced, light-induced vegetative pigmentation, was used to investigate how high light affects anthocyanin biosynthesis, and to assess the effects of anthocyanin pigmentation upon photosynthesis. Lc petunia plants displayed intense purple anthocyanin pigmentation throughout the leaves and stems when grown under high-light conditions, yet remain acyanic whe...

Status of individual animals is often shown in pigmentation. For instance, stress responsiveness is associated with melanin-based pigmentation in vertebrates in general. This pattern is evident in Atlantic salmon (Salmo salar) and rainbow trout (Onchorhynchus mykiss) with melanin-based spots indicating stress coping style. Arctic charr (Salvelinus alpinus) differ from other salmonids in pigment...

Pigmentation varies within and between species and is often adaptive. The amount of pigmentation on the abdomen of Drosophila melanogaster is a relatively simple morphological trait, which serves as a model for mapping the genetic basis of variation in complex phenotypes. Here, we assessed natural variation in female abdominal pigmentation in 175 sequenced inbred lines of the Drosophila melanog...

Using quantitative trait locus (QTL) mapping, we studied the genetic basis of the difference in pigmentation between two sister species of Drosophila: Drosophila yakuba, which, like other members of the D. melanogaster subgroup, shows heavy black pigmentation on the abdomen of males and females, and D. santomea, an endemic to the African island of São Tomé, which has virtually no pigmentation. ...

BACKGROUND Although, melasma is most prevalent among Asian young women, and also darkly pigmented individuals are particularly prone to developing post inflammatory hyperpigmentation, to the best of our knowledge, there are rare or no studies about the association of melasma and Post inflammatory hyperpigmentation. OBJECTIVES The aim of this study was to investigate how likely is a melasma pa...