Epidemiological studies have identified low-density lipoproteins (LDL) and high-density lipoproteins (HDL) as independent risk factors that modulate cardiovascular disease (CVD) risk.1,2 Over the past decade, clinical trials of LDL-lowering drugs have clearly established that reductions in LDL are associated with a 30% to 45% reduction in clinical events.3–7 However, despite lowered LDL, many p...

SHROB rats have been suggested as a model for metabolic syndrome (MetS) as a situation prior to the onset of CVD or type-2 diabetes, but information on descriptive biochemical parameters for this model is limited. Here, we extensively evaluate parameters related to CVD and oxidative stress (OS) in SHROB rats. SHROB rats were monitored for 15 weeks and compared to a control group of Wistar rats....

Heat acclimatization improves thermoregulatory responses to heat stress and decreases sweat sodium concentration ([Na(+)](sweat)). The reduced [Na(+)](sweat) results in a larger increase in plasma osmolality (P(osmol)) at a given amount of sweat output. The increase in P(osmol) inhibits thermoregulatory responses to increased body core temperature. Therefore, we hypothesized that the inhibitory...

BACKGROUND A link between uric acid (UA) levels and cardiovascular diseases has been previously reported. However, its importance as a risk factor is still controversial. This study sought to determine whether elevated serum uric acid levels are associated with cardiovascular disease (CVD) in middle-aged and elderly Chinese individuals. METHODS We conducted a population-based cross-sectional ...

Background: A growing number of patients with End-Stage Renal Disease (ESRD) are undergoing long-term hemodialysis (HD). HD needs a vascular access (VA) and complications of VA account for a sizable proportion of its costs. One of the important cardiovascular diseases (CVD) is atherosclerosis, which is a major cause of premature deaths in the world. So, it is essential to find the risk factors ...

Several kinds of chemical vapor deposition (CVD) methods have been extensively used in the semiconductor industries for bulk crystal growth, thin film deposition, and nanomaterials synthesis. In this article, we focus on microwave-excited surface wave plasma CVD (MW-SWP CVD) method growth graphene related materials. The MW-SWP system consisting waveguide, slot antenna, dielectric windows is sig...

CARDIOVASCULAR disease (CVD) is a major cause of morbidity and mortality after renal transplantation (RT). The excess risk of CVD in RT is due in part to a higher prevalence of established atherosclerotic risk factors, including hypertension, dyslipidemia, diabetes, obesity, and physical inactivity. However, some renal-related risk factors like immunosuppressive medication and residual renal in...

We investigate the associations of three established plasma biomarkers in the context of HIV and treatment-related variables including a comprehensive cardiovascular disease risk assessment, within a large ambulatory HIV cohort. Patients were recruited in 2010 to form the Royal Perth Hospital HIV/CVD risk cohort. Plasma sCD14, sCD163 and CXCL10 levels were measured in 475 consecutive patients w...

Sputter erosion depths in Si films deposited on Al substrates by PVD, CVD and plasma spay methods were measured after exposure to As+ ions a DC implanter beam Ga+ with scanned FIB. Erosion are optical methods. Metallic contamination the RBS. surface textures examined SEM.

Shexiang Baoxin Pill (SBP), a traditional Chinese medicine formula, is commonly used to treat cardiovascular disease (CVD) in China. However, the complexity of composition and targets has deterred our understanding of its mechanism of action. Using network pharmacology-based approaches, we established the mechanism of action for SBP to treat CVD by analyzing protein-protein interactions and pat...