Therapeutic plasma exchange (TPE) is indicated as a treatment for wide array of diseases, extensively addressed in the Guidelines American Society Apheresis. In pregnancy, TPE an uncommon event and application largely based on extrapolation efficacy safety non-pregnant population. This review intends to describe currently available experience pregnancy help clinicians recognise indications duri...

Ultracentrifugal analysis of the plasma of squirrel monkeys at various times after the injection of [Me-(14)C]choline revealed the specific activities of lecithin in both high (HDL) and low (LDL) density lipoproteins to be similar. This was also true for sphingomyelin. The exchange of phospholipids in vitro was studied by incubating unlabeled plasma with labeled LDL and HDL isolated 40 hr after...

Initial management of patients with thrombotic thrombocytopenic purpura–hemolytic uremic syndrome (TTP-HUS) is difficult because of lack of specific diagnostic criteria, high mortality without plasma exchange treatment, and risks of plasma exchange. Although severe ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type 1 repeats) deficiency may be specific for TTP, the role o...

Objective. Report of a case of catastrophic antiphospholipid syndrome (CAPS) with multiple organ involvement leading to a life-threatening condition despite early combination corticosteroid and heparin therapy. Initiation of plasma exchange led to rapid improvement of the patient's general condition. Design. CASE REPORT Setting. University teaching hospital medical intensive care unit. Patien...