Few studies have assessed how ploidy type within a species affects genetic variation among populations in relation to source climates. Basin wildrye (Leymus cinereus (Scribn. & Merr.) A. Love) is a large bunchgrass common in the intermountain Western U.S. found in both octoploid and tetraploid types. In common gardens at two sites over two years differences in both ploidy type and genetic varia...

OBJECTIVES The common subtypes of renal tumors are conventional or clear cell carcinoma, papillary carcinoma, chromophobe carcinoma and oncocytoma. Each subtype has its distinct histogenesis and clinical evolution. DNA ploidy is viewed as a marker of gross genomic aberrations. The aim of this study is to evaluate the DNA ploidy in the common subtypes of renal tumors to increase our understandin...

Cancer cells can undergo stress-induced premature senescence, which is considered to be a desirable outcome of anticancer treatment. However, the escape from senescence and cancer cell repopulation give rise to some doubts concerning the effectiveness of the senescence-induced anticancer therapy. Similarly, it is postulated that polyploidization of cancer cells is connected with disease relapse...

Sugarcane is a major crop for sugar production around the world. The complexity of sugarcane genome creates challenges use both conventional and molecular breeding methods to improve at genetic level. DNA sequencing an important tool assess how genus Saccharum genera complex are interrelated. Here, we identify kinship Nepal2013-6 (Saccharum spontaneum, x = 10) using tetra-primer amplification r...

OBJECTIVE We investigated the correlation between ploidy or S-phase fraction (SPF) and the clinical pathological characteristics of patients with peritoneal carcinomatosis from ovarian cancer. We also assessed their relation with the in vivo and in vitro response to several chemotherapeutic agents. PATIENTS AND METHODS Fifty-three patients with peritoneal carcinomatosis from ovarian cancer we...

ploidy with a DNA index of 1.9 was detected in only 1 patient. This patient, who had a stage IA serous BOT, is alive without any recurrence after 96 months of observation following TAH/BSO. All the remaining 69 tumours showed diploid DNA content. The coefficient of variation for the diploid peaks ranged from 7.48 to 12.8 (mean 8.67) in diploid histograms despite using a low flow rate. A recent ...

Polyploid plants often have higher biomass and superior crop qualities. Breeders therefore search for crop germplasm with higher ploidy levels; however, whether higher ploidy levels are associated with better performance remains unclear. Actinidia arguta and related species, whose commercialized fruit are referred to as kiwiberries, harbor a series of ploidy races in nature, offering an opportu...

Differential diagnostics of borderline ovarian tumours and ovarian carcinomas is generally based on morphological criteria, which are not always sufficient for final diagnosis. Therefore, we investigated the practical diagnostic application of the CAS200 image analyzer and new ploidy-related parameters in a series of 68 borderline tumours and 42 low-grade carcinomas of the ovary. Highly signifi...