Two azide analogues of ketanserin (6- and 7-azido-3-[2- [4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2, 4(1H,3H)-quinazolinedione) were synthesized and tested as possible photoaffinity probes for serotonin-S2 and histamine-H1 receptors. In reversible binding experiments, the azides showed high affinity for both receptor types. When membrane preparations were incubated with nanomolar concentrations...

Sloane, Crane, and Mayer (2) reported that Mycobacterium smegmatis oxidizes aniline to p-aminophenol. It was also shown (2) that p-aminobenzoic acid (PABA) yields p-aminophenol after the PABA is first enzymatically decarboxylated to aniline. It is the purpose of this publication to present data on the effect of pH, citrate, inorganic ions, and inhibitors on this hydroxylation reaction. The data...

Antimicrobial surfaces can be applied to break transmission pathways in hospitals. Polyaniline (PANI) and poly(3-aminobenzoic acid) (P3ABA) are novel antimicrobial agents with potential as non-leaching additives to provide contamination resistant surfaces. The activity of PANI and P3ABA were investigated in suspension and as part of absorbent and non-absorbent surfaces. The effect of inoculum s...

Only in liquid environment can most biomolecules maintain their biological activity, the realization of terahertz (THz) spectrum detection water-bearing has an important application value for research function and structure active non-invasive biomedical detection. In this paper, by using THz radiation source generated LiNbO3 light rectification, combing with local electric field enhancement ef...

We report on nanoindentation data for two pairs of polymorphic compounds p-aminobenzoic acid (pABA) and p-nitrobenzoic (pNBA) compare it with existing in the literature. also explore a new parameter, s-PBC, as tool to estimate hardness.