An investigation into the suitability of mucuna gum microspheres for oral delivery of glibenclamide is presented. Mucuna gum microspheres were formulated under different conditions of polymer concentration and crosslinking time at constant speed. The formulated microspheres were thereafter loaded with glibenclamide by the remote loading process. The microspheres were evaluated according to part...

Interpenetrating polymer network of cross-linked blend microspheres for controlled release Acebutolol HClP. Ramakrishna, B. Mallikarjuna, A. Chandra Babu, P. Sudhakar, K. Chowdoji Rao, M.C.S. Subha

Microspheres are multiparticulate drug delivery systems that distribute medications at a predetermined rate to specific region. free-flowing powders manufactured from biodegradable proteins or synthetic polymers, with particle sizes ranging 1 1000 micrometers. Benefits of using microspheres in medication delivery, bone tissue manufacture, and pollutant absorption desorption by regeneration .The...

A facile and efficient hard-templating strategy is reported for the preparation of porous nickel microspheres with excellent uniformity and strong magnetism. The strategy involves impregnation of porous polymer microspheres with nickel precursors, calcination to remove the template, followed by thermal reduction. The morphology, structure, and the property of the Ni microspheres were characteri...

Microspheres constitute an important part of novel drug delivery system by virtue of their small size and efficient carrier capacity. Due to their short residence time, bioadhesive characteristics can be coupled to microspheres to develop mucoadhesive microspheres. Bioadhesion can be defined as the state in which two materials, at least one of which is biological in nature, are held together fo...

The objective of this work was to develop and evaluate reconstitutable suspensions of ibuprofen-loaded microspheres prepared with an acrylic polymer (Eudragit RS-PM). The microspheres were prepared by the quasi-emulsion solvent diffusion technique. To prepare reconstitutable suspension formulation, the microspheres used had a mean particle size of 316.6 microm and 99.8% loading efficiency. Xant...

Microspheres containing indinavir sulfate were prepared by the emulsion solvent evaporation technique using surfactant sorbitan monooleate 80. The evaluation reports for Fourier-transform infrared spectroscopy and X-ray diffraction taken to see whether altered physicochemical features of produced microspheres. Scanning electron microscopy was used observe surface topography When 80 employed at ...