Dengue viral infection is on the rise in tropical urban and semi-urban parts of the world. WHO fact sheetN°117 updated in May 2015 estimates 390 million dengue infections per year and that 3900 million people, in 128 countries, are at risk. The WHO case definition of severe dengue includes organ impairment, but does not describe neurological manifestations as a separate entity. Earliest reports...

The paper on nerve conduction studies (NCS) and current perception thresholds (CPT) in workers assessed for hand-arm vibration syndrome (HAVS) by Lander et al. [1] while informative contained several oversights about the CPT neurophysiological test that would bias any reader's interpretation of the findings. The standardized automated double-blind CPT evaluation provides a painless objective ne...

Background and purpose Measurement of the cross-sectional area (CSA) cervical nerve roots using ultrasound is useful in evaluation inflammatory polyneuropathies, measurement CSA vagal might give information about involvement autonomic nervous system. We performed a systematic review meta-analysis published reference values for nerve. Methods included available-to-date studies on healthy adults ...

Charcot-Marie-Tooth neuropathy type 4 (CMT4) comprises a large group of genetically heterogeneous progressive sensory motor neuropathies characterized by autosomal recessive inheritance. Among these, CMT4B includes 3 forms related to genes of the myotubularin family, namely CMT4B1 (MTMR2), CMT4B2 (MTMR13/SBF2), and CMT4B3 (MTMR5/SBF1).

1 Indiana University School of Medicine, 1120 W. Michigan Street, Suite 200, Indianapolis, IN 46202, USA 2Division of Otolaryngology, Penn State Milton S. Hershey Medical Center, 100 Campus Drive, Suite 400, Hershey, PA 17033, USA 3King’s College London School of Medicine, Strand, London WC2R 2LS, UK 4Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders...

Results Seventeen patients were studied. All were Jews. Eleven were of Yemenite descent, harboring the ser77tyr mutation. Of these, seven belonged to a large 3-generation family, and each of the other four to different unrelated families. Three patients were Ashkenazi; one carried the val30met mutation, another the phe33leu mutation, and the third had two mutations on one allele: phe33Ile and g...

BACKGROUND Higher plantar pressures play an important role in the development of plantar foot ulceration in diabetic polyneuropathy and earlier studies suggest that higher pressures under the forefoot may be related to a decrease in lower leg muscle strength. Therefore, in this randomised controlled trial we evaluated whether lower-extremity strength training can reduce plantar pressures in dia...