PURPOSE The ocular humors are relatively low in protein, yet cell growth in the human capsular bag still occurs after extracapsular cataract extraction (ECCE) surgery. This resilient growth gives rise to posterior capsule opacification (PCO) in a significant proportion (30%) of patients. This study compared the ability of human lens cells to proliferate in serum-supplemented and protein-free me...

PURPOSE To evaluate posterior capsule opacification (PCO) in humans after cataract surgery with intraocular lens (IOL) implantation, by using optical coherence tomography (OCT-1). METHODS Sixty-six eyes with PCO and 20 eyes with a normal posterior capsule were analyzed. A 3-mm-long horizontal scan of the posterior capsule was obtained. Measurements at three points and their average were recor...

AIM To analyze clinical outcomes and complications after traumatic cataract extractions because of post-traumatic lens opacification. METHODS We performed a retrospective analysis of 24 eyes with traumatic cataract surgically treated between May 2000 and June 2003. Preoperative visual acuity, postoperative best corrected visual acuity, and preoperative, intraoperative, and postoperative compl...

The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens. The factor indicating the biocompatibility of an intraocular lens is the behavior of inflammatory and lens epithelial cells. Hence, the biocompatibility of intraocular lens materials is assessed in...

Proteins in basement membrane (BM) are long-lived and accumulate chemical modifications during aging; advanced glycation endproduct (AGE) formation is one such modification. The human lens capsule is a BM secreted by lens epithelial cells. In this study, we have investigated the effect of aging and cataracts on the AGE levels in the human lens capsule and determined their role in the epithelial...

PURPOSE To investigate the effect of distilled deionized water (DDW) on lens epithelial cells (LECs) attached to the lens capsule. SETTING Wound Healing Research Laboratory, Center for Vision Research, Westmead Hospital, Sydney, NSW, Australia. METHODS Anterior capsulotomy specimens taken during routine cataract surgery were divided in half. One half was immersed in DDW and the other half i...

UNLABELLED It has been suggested that a clear anterior nasal capsule contributes to negative dysphotopsia and that symptoms may resolve with opacification of the capsule. We describe a case in which negative dysphotopsia occurred despite a translucent anterior peripheral capsule and resolved following laser removal of the anterior nasal capsule. FINANCIAL DISCLOSURE No author has a financial ...