نتایج جستجو برای: pou1f1 gene
تعداد نتایج: 1141410 فیلتر نتایج به سال:
Introduction: The POU class 1 homeobox 1 transcription factor (POU1F1, also known as Pit-1) is expressed in the mammary gland and its overexpression induces profound phenotypic changes in proteins involved in cell proliferation, apoptosis, and invasion. Patients with breast cancer and elevated expression of Pit-1 show a positive correlation with the occurrence of distant metastasis. In this stu...
هدف اصلی و اولیه این مطالعه, بهینه سازی انتقال ژن به قارچ بیماریزای گیاهی fusarium graminearum بود که عامل اصلی بیماری بلایت فوزاریومی سنبله (fhb) در غلات دانه ریز است. تراریخت کردن ژنتیکی، نه تنها ابزاری مفید جهت شناسایی ژنوم و مطالعه عملکرد آنها در بیمارگرهای گیاهی است, بلکه زمینه مطالعه برهمکنش گیاه - بیمارگر و راهکار لازم برای مقابله با بیماری را فراهم می کند. علاوه براین, تراریختی قارچ ها ...
Chinese hamster ovary (CHO) cells are resistant to infections by gibbon ape leukemia virus (GALV) and amphotropic murine leukemia virus (A-MLV) unless they are pretreated with tunicamycin, an inhibitor of N-linked glycosylation. These viruses use the related sodium-phosphate symporters Pit1 and Pit2, respectively, as receptors in nonhamster cells, and evidence has suggested that the correspondi...
Polish Red (PR) is the native Polish cattle breed included in the FAO National Rare Livestock Breeds Preservation Programme. The breed is characterized by high vitality and fertility, calving ease, resistance to diseases, and low requirements for feed. Milk yield is low, but fat and protein content of milk are high. The frequencies of alleles of commonly studied loci as well as the presence of ...
polymyxa betae keskin یکی از مهمترین ناقلین بیماریهای ویروسی خاکزاد چغندرقند است.این ناقل متعلق به سلسله protozoa و شاخه plasmodiophoromycota بوده و قادر است ،5 نوع بیماری ویروسی مختلف را به چغندرقند منتقل نماید که یکی از مهمترین آنها، بیماری ریشه ریشی یا رایزومانیا است که توسط ویروس) bnyvv beet necrotic yellow vein virus( ایجاد می شود. این بیماری ویروسی انتشارجهانی داشته و در استان های خراسان ...
Thyrotropin-releasing hormone (TRH) activates not only the secretion of thyrotropin (TSH) but also the transcription of TSHβ and α-glycoprotein (αGSU) subunit genes. TSHβ expression is maintained by two transcription factors, Pit1 and GATA2, and is negatively regulated by thyroid hormone (T3). Our prior studies suggest that the main activator of the TSHβ gene is GATA2, not Pit1 or unliganded T3...
the effect of mdma and pentoxifylline drug on bad/bcl-xl gene dosage expression changes on rat liver
mdma generally known as ecstasy, have deleterious effects on the serotonergic neurotransmitter system. recent findings suggest that the liver and brain are major target organs of mdma-related toxicities. although most research is being dynamically performed on brain, however, the molecular mechanisms by which mdma elicits adverse effects in both organs are poorly undrestood.the present study wa...
background 3-4methylenedioxymethamphetamine (mdma) is a synthetic and psychoactive drug, which is known popularly as ecstasy and has toxic effects on human organs. objectives considering the potential toxic interaction, this study was performed to quantify the expression of bax and bcl2 genes in mdma-induced hepatotoxicity on rat liver. subsequently, we evaluated pentoxifylline as a possible pr...
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