نتایج جستجو برای: pre formulation
تعداد نتایج: 420673 فیلتر نتایج به سال:
Problem formulation is an important part of the design process that has been largely underexplored. Similarly, the relationship between how designers formulate problems and creative outcome is not well understood. To shed light on what the process of problem formulation can tell us about creativity in design, we use the problem map model – a flexible, domainindependent ontology for modeling the...
INTRODUCTION This study describes a pivotal clinical trial of a new minimally invasive mesotherapy technique for facial rejuvenation. METHODS The authors utilized two formulations: formulation A with hyaluronic acid, vitamins, amino acids, minerals, coenzymes, and antioxidant substances; formulation B with hyaluronic acid and idebenone. Fifty participants were enrolled in the study and divide...
PURPOSE Generic substitution of brand-name medications can lead to significant cost savings and is an accepted medical practice. This study evaluated clinical and safety outcomes among liver transplant recipients whose mycophenolate mofetil (MMF) was converted from the brand-name formulation (Cellcept) to a generic formulation (My-rept). METHODS Clinical data from multiple centers were prospe...
We present a methodology for scalable exploration of cyber-physical system architectures. propose mathematical formulation the architecture problem as an optimized mapping that includes joint selection topologies and components taken from pre-defined libraries. Using graph-based representation architecture, we introduce novel compact encodings constraints path significantly improve scalability ...
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To accelerate the clinical development of this promising agent, we designed and conducted the first-ever phase 0 chemoprevention trial to evaluate and compare the effects of food and formulation on SR13668 bioavailability. Healthy adult volunteers were randomly assigned to ...
a r t i c l e i n f o a b s t r a c t Keywords: Magnetic confinement fusion Halo currents Neumann boundary value problem Elliptic partial differential equations Complementarity Mixed-hybrid formulation Lazy cohomology generators This paper addresses the calculation of the resistive distribution of halo currents in three-dimensional structures of large magnetic confinement fusion machines. A Neu...
Bi-layered [1] tablet refers to tablet which contain subunits. In bi-layer [2] tablets, one layer tablet provides immediate release and the other layer acts as sustained release. Sumatriptan is a new class of anti-migraine [3] drugs that selectively activate 5-HT1B/1D receptors and are called triptans. Our objective is to formulate and evaluate the bi-layer tablets of sumatriptan succinate of d...
Liposomes are widely used as drug delivery systems in different forms including osmotic pumps, infusion and IV injection. In spite of these, there is no data available about their behavior under convective flow (e.g. infusion or osmotic pumps) and upon stagnation in such drug delivery systems. As a part of a series of investigations in this area, the present study investigates the effects of vi...
We give a pedagogical introduction to the Hamiltonian formalism of general relativity at an advanced undergraduate and graduate levels. After covering mathematical pre-requisites as well $3+1$-decomposition spacetime, we proceed discuss Arnowitt-Deser-Misner (ADM) (a approach) relativity. Then brief but self-contained homogeneous (but not necessarily isotropic) universes associated Bianchi clas...
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