Despite the important advances in perinatal care in the past decades, asphyxia remains a severe condition leading to significant mortality and morbidity. Perinatal asphyxia has an incidence of 1 to 6 per 1,000 live full-term births, and represents the third most common cause of neonatal death (23%) after preterm birth (28%) and severe infections (26%). Many preconceptional, antepartum and intra...

BACKGROUND The aim of the study was to determine the incidence of neural tube defects (NTD) among admissions at a regional referral hospital in Saudi Arabia, compare trends over several years and note any influence of prenatal folic acid treatment. PATIENTS AND METHODS For every NTD admission into the newborn unit of Asir Central Hospital, during the period January 1995 through December 1998,...

Introduction Pregnancies affected with neural tube defects (NTDs) are mostly associated to maternal deficiency of folic acid (FA). Although supplementation is recommended for all women of childbearing age, the incidence of NTDs in Puerto Rico has not shown a significant decrease. Objective The goal of this study was to assess the awareness and level of knowledge of FA supplementation among wo...

BACKGROUND Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic machinery. Besides in vitro environmental exposures, the possible impact on the reprogramming of methylation profiles at imprinted genes ...

OBJECTIVE To investigate the feasibility of improving screening for carriers of haemoglobin disorders in general practice by using a nurse facilitator to work with primary care teams and the relevant haematology laboratories; to identify problems in communication between all those involved in delivering the service, and to implement solutions. DESIGN Two year, practice based randomised contro...

introduction: health care industry consists of an unexpected and confusing environment in which quality events play the important role. in such conditions, the necessary changes should be made. excellence models are general oriented frameworks that are able to achieve the above intention. materials & methods: this study is a descriptive cross-sectional study. data gathered by a standard checkli...

OBJECTIVE High parity and short birth intervals among Hispanic women may deplete their folic-acid levels and place them at risk for neural tube defects (NTDs). The purposes of this study were to evaluate factors associated with multivitamin supplementation rates during the early (one to six weeks) postpartum period among Mexican-origin women and present their implications in preventing NTDs in ...

Pregnant women with epilepsy constitute 0.5% of all pregnancies. Proper seizure control is the primary goal in treating women with epilepsy. The commonly used anticonvulsants are established human teratogens. Factors such as epilepsy, anticonvulsant-induced teratogenicity, patient's genetic predisposition and the severity of convulsive disorder may attribute to adverse pregnancy outcome for the...

BACKGROUND In vitro fertilisation (IVF) treatment provides an opportunity to study early developmental responses to periconceptional dietary interventions. Retrospective studies have suggested links between preconception diet and fertility, and more recently, a "Mediterranean" diet has been reported to increase pregnancy rates by up to 40%. In addition, a prospective study examining increased i...