نتایج جستجو برای: precursor b
تعداد نتایج: 954137 فیلتر نتایج به سال:
In a review of 432 children with newly diagnosed acute lymphoblastic leukemia (ALL), we identified a new nonrandom translocation. tdic(9;12)(pl ?1 ;pl ?2). in the leukemic marrow cells of eight patients. Seven had hypodiploid karyotypes that lacked chromosomes 9 and 1 2 and contamed a der(12), tdic(9;12); the eighth had a pseudodiploid karyotype with two normal 9 chromosomes, one normal 12 and ...
From the *Leuhaemia Research Fund Centre, Institute of Cancer Research, London SW3 6JB; the eMRC Radiobiology Unit, Didcot 0XI10Rs United Kingdom; the $Oncogene and Tumor Suppressor Gene Program, La Jolla Cancer Research Foundation, La Jolla, California 92037; and the IIDepartment of Medicine, Microbiology and Immunology, Howard Hughes Medical Institute, Washington University School of Medicine...
The main component of Alzheimer’s disease (AD) senile plaques is amyloid-b peptide (Ab), a proteolytic fragment of the amyloid precursor protein (APP). Platelets contain both APP and Ab and may contribute to the perivascular amyloid deposition seen in AD. However, no data are available concerning the biochemical mechanism(s) involved in their formation and release by these cells. We found that ...
Precursor B-cell lymphoblastic lymphoma (B-LBL) is an uncommon subtype of Non-Hodgkin lymphoma (NHL), accounting for only 0.3% of NHL in adults and less than 10% of all LBL cases. Unlike T-cell LBL, it usually presents with extranodal involvement while sparing the bone marrow (BM). Among the 27 patients with LBL treated in the Asan Medical Center between January 2007 and March 2012, 3 had B-LBL...
The rearrangement patterns of Ig and T-cell receptor (TcR) genes were studied by Southern blot analysis in 30 precursor B-cell acute lymphoblastic leukemias (B-ALLs) and 10 T-ALLs at diagnosis and subsequent relapse. Eight precursor B-ALLs appeared to contain biclonal/oligoclonal Ig heavy-chain (IgH) gene rearrangements at diagnosis. Differences in rearrangement patterns between diagnosis and r...
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