Pregnancy-associated plasma protein-A (PAPP-A) level is an independent predictor of acute cardiovascular event occurrence. To test the hypothesis that increased PAPP-A levels would be associated with a higher burden of coronary thin-cap fibroatheroma (TCFA) thereby underlying the heightened risk for cardiovascular events in patients with coronary artery disease; 154 patients (462 vessels and 97...

Introduction. Annually, more than 13 million neonates are born with fetal growth retardation (FGR) worldwide. FGR increases prenatal mortality and morbidity. Due to no effective treatments for available, its prevention prognosis of extreme relevance. Aim: development prognostic clinical anamnestic mathematical model assessing a risk developing during pregnancy. Materials Methods. A prospective,...

background: pregnancy is associated with unfavorable metabolic profile, which might in turn result in adverse pregnancy outcomes. the current study was designed to evaluate the effects of calcium plus vitamin d administration on metabolic status and pregnancy outcomes in healthy pregnant women. methods: this randomized double‑blind placebo‑controlled clinical trial was performed among 42 pregna...

Plasma volume expansion has been associated with fetal growth. Our objective was to examine the associations between maternal nutritional status in early pregnancy and extracellular water (ECW), total body water (TBW), and percentage plasma volume change across pregnancy. In a subsample of 377 pregnant women participating in a cluster-randomized trial of micronutrient supplementation, hemoglobi...

To study the influence of season on oxidative status of buffalo semen and their association with semen characteristics and seminal plasma proteins, ejaculates were collected twice a week in winter, summer and rainy seasons from six adult Bhadawari buffalo bulls. The neat semen was analyzed for semen characteristics immediately after collection and oxidative status viz. lipid peroxidation (LPO),...

we encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. this child was being fed with a low-protein diet when the skin disorder developed. a deficiency in plasma levels isoleucine, was confirmed. supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. we assume that in our patient the sk...

Background and aims: Normal pregnancy and its successful outcome require intake of sufficient food. Undesirable nutrition is directly associated with pregnancy outcome, therefore, its prevention is the best strategy to maintain maternal and fetal health. The present study was conducted to investigate the prevalence of malnutrition during pregnancy and associated factors in women of Ard...