نتایج جستجو برای: prenylation
تعداد نتایج: 805 فیلتر نتایج به سال:
The putative prenyltransferase gene ACLA_031240 belonging to the dimethylallyltryptophan synthase superfamily was identified in the genome sequence of Aspergillus clavatus and overexpressed in Escherichia coli. The soluble His-tagged protein EAW08391 was purified to near homogeneity and used for biochemical investigation with diverse aromatic substrates in the presence of different prenyl dipho...
Introduction In recent years, covalent modification of proteins by lipi'ds has been found to be a more frequent modification than originally anticipated [ 11. Three major classes of such modifications have been particularly well characterized. These are: (a) the N-terminal myristoylation of glycine residues through amide linkage; (b) the prenylation of cysteine residues, located in C-terminal d...
The structure-function correlation of membrane proteins have been a difficult task, particularly in context to transient protein complexes. The molecular simulation of ternary complex of Rab7::REP1::GGTase-II was carried out to understand the basic structural events occurring during the prenylation event of Rab proteins, using the software YASARA. The study suggested that the C-terminus of Rab7...
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