INTRODUCTION Engineered tissues offer strong possibilities as model systems for studying tissue responses to physical, chemical or biological stimuli. Moreover, they can be used to investigate specific pathologies or clinical treatments with less ethical considerations and better experimental control than animal models or human studies. We use the concept of tissue engineering to design in-vitr...

(1) An acute phagedenic ulcer, circular in outline with sharp punched out edges usually commencing on the site of some trivial abrasion not necessarily of recent origin. The rapid increase in area and depth of the ulcer was appalling. Within 24 or 48 hours a trivial abrasion might become an ulcer as big as a rupee and with deep fascia exposed in its base. Considerable swelling of surrounding ti...

Cold sores are caused by a herpes virus, most often the herpes simplex 1 virus. Cold sores should not be confused with canker sores, which are small ulcerations in the mouth. Rather, cold sores are fluid-filled blisters that form on the gums and the outside of the mouth and lips. The blisters, which are contagious, later break, ooze, and crust over before healing. Recurrences are common and can...

The inflammatory and repair processes are no longer simple events to describe in the light of the ever increasing knowledge in this field. This review is only a brief resume of the salient events associated with tissue repair, with an emphasis on the soft tissues rather than the classical 'wounds' approach. I have covered the electrical stimulation modalities for wound healing (ulcers, pressure...

The clinician providing seating for patients who are unwell, who have poor functional ability or who are at risk of pressure sores, is faced with an increasing choice of products. Making the decision as to which product and associated features to choose can be a difficult task. This article describes the importance of suitable seating provision in patients who are at risk and outlines the Karom...

Mr J. M. Cotterill exhibited a patient after LAMINECTOMY FOR PARALYSIS of two years' standing, the result of spinal caries. The symptoms of spinal mischief began when the patient was set. 36, and signs of pressure on the cord developed rapidly. For six months before the operation there had been complete motor and sensory paralysis of the lower half of the body. There was incontinence of urine a...