Two new samples of poly(amide-imide)/nanocomposites containing bicyclo segment and dibenzalaceton moiety in the main chain were synthesized by a solution intercalation technique. Poly(amide-imide) (PAI) 8 as a source of polymer matrix was synthesized by the direct polycondensation reaction of N,N´-bis(4-carboxyphenyl)bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic diimide 3 with 2,6-bis(4-amino...

Five new aromatic poly(amide-imide)s (5a-e) were synthesized by direct polycondensationreaction of N-(4-carboxy phenyl) trimellitimide (3) with five aromatic diamines (4a-e) by usingtriphenyl phosphite in N-methyl-2-pyrrolidone (NMP) and pyridine at solution containingdissolved CaCl2. All of the polymers were obtained in quantitative yields with inherentviscosities between 0.29-0.40 dL/g. The r...

The influence of alkyl 3-position substituents on the rate of amide isomerization N-terminal to proline and hydroxyproline has been explored via the synthesis and analysis of (2S)-N-(acetyl)proline N′-methylamide (1), (2S,4R)and (2S,4S)-N-acetyl-4-hydroxyproline N′-methylamides 2 and 3, and their respective 3,3-dimethyl analogues 4-6. The relative populations of the amide cis and trans isomers ...

Previous studies have revealed that the glucoincretin hormone glucagon-like peptide-1 (GLP-1)(7-36)amide is metabolized by dipeptidyl peptidase-IV (DPP-IV) and neutral endopeptidase 24.11 (NEP) to yield GLP-1(9-36)amide and GLP-1(28-36)amide, respectively, as the principal metabolites. Contrary to the previous notion that GLP-1(7-36)amide metabolites are pharmacologically inactive, recent studi...

Developing mild and efficient catalytic methods for the selective synthesis of amines is a longstanding research objective. In this respect, deoxygenative amide reduction has proven to be promising but challenging, as approach necessitates C–O bond cleavage. Herein, we report hydroboration primary, secondary, tertiary amides at room temperature catalyzed by an earth-abundant-metal catalyst, Zr-...

The title mol-ecule, C(26)H(22)N(4)O(2), is centrosymmetric and adopts an anti conformation. Two intra-molecular hydrogen bonds, viz. amide-pyridine N-H⋯N and phen-yl-amide C-H⋯O, stabilize the trans conformation of the (pyridine-2-carboxamido)-phenyl group about the amide plane. In the crystal, the presence of weak inter-molecular C-H⋯O hydrogen bonds results in the formation of a three-dimens...

The thio-amide and quaternary amine parts of the title compound, C(6)H(15)N(2)S(+)·Cl(-), are mutually almost perpendicular, the dihedral angle being 80.6 (7)°. The thio-amide group is planar and adopts a Z conformation, whereas the amine end of the cation is in an extended conformation. In the supra-molecular structure, mol-ecules are linked into centrosymmetric dimers by two hydrogen bonds: N...

The rational design of heterometallic compounds bearing s-block metal ions have been a difficult task for chemists owing to their lack preferential geometries. However, some strategies, such as the coordinating pockets with different sizes and/or donor atoms, offered great results. In this work, strategy has tested using Ca(II) an ion and compound previously obtained by our group formula [Zn3(μ...

Structures of three cocrystals nootropic racetams were studied. They included two phenylpiracetam (PPA) with 4-hydroxybenzoic acid (HBA) different stoichiometries, PPA·HBA and PPA·2HBA, cocrystal 2-(4-phenyl-2-oxopyrrolidin-1-yl)-N’-isopropylideneacetohydrazide (PPAH) 4-hydroxybenzamide (HBD), PPAH·HBD·(acetone solvate). X-ray study the pure forms PPA PPAH was also carried out to identify varia...