Systemic amyloid light chain (AL) amyloidosis (previously known as primary amyloidosis) is a multisystem disease characterized by the extracellular deposition of fibrils composed of immunoglobulin light chains within various organs. AL amyloidosis is associated with different types of monoclonal plasma cell dyscrasias, including multiple myeloma and other monoclonal gammopathies.1 Cardiac invol...

A rotationally-symmetrical ellipsoidal flow model is proposed for the relativistic heavy-ion collisions and compared with the 14.6 A GeV/c Si-Al and 10.8 A GeV/c Au-Au collision data. The large stopping in the heavier collision system and heavier produced particles is accounted for by using the ellipsoidal flow picture. The central dip in the proton and deuteron rapidity distributions for Si-Al...

The first absorption spectra recorded in Europe using synchrotron radiation as the X-ray source were the K-edge of Al and the LIII-edge of Cu taken at Frascati electron synchrotron in May 1963 by the French-Italian group comprised of Y. Cauchois, C. Bonnelle and G. Missoni.

Pleural effusion is a common problem dealt by most of the practicing clinicians. Some causes for pleural effusion are less often considered as a differential diagnosis owing to its rarity. Here we report a case of renal amyloidosis on alternate day haemodialysis for about two months time presenting with left sided pleural effusion. On evaluation this turned out to be a case of amyloidosis on th...

The clinical details and post-mortem findings are given of a patient who had primary ;acquired' hypogammaglobulinaemia and was found at necropsy to have amyloidosis. The relationship of gamma globulin deficiency to amyloidosis is discussed, and the possible relevance of the hypogammaglobulinaemia to the formation and nature of amyloid is noted. It is suggested that a disordered immune response ...

Primary localized cutaneous amyloidosis (PLCA) is caused by the extracellular deposition of amyloid material in the skin without other cutaneous or systemic organ involvement. PCLA is classified into lichen, macular,and nodular amyloidosis. Macular amyloidosis and lichen amyloidosis are named as biphasic amyloidosis when they are concurrently seen in a patient. The treatment of this disease is ...

The existence of multipole surface-plasmon modes at simple-metal surfaces is demonstrated both experimentally and theoretically. Inelastic reAection electron-scattering experiments on smooth films of K and Na show loss peaks originating from the ordinary surface plasmon as well as from a higher-energy multipole mode. Microscopic density-functional calculations of the electron-loss function repr...

Mutation Screening of the Factor VIII Gene in Hemophilia A in Saudi Arabia: Two Novel Mutations and Genotype-Phenotype Correlation Faisal A Al-Allaf1,2,3#, Mohiuddin M Taher3#*, Zainularifeen Abduljaleel3, Mohammad Athar3, Faisal A Ba-hammam3, Munir Abdulla3, Abdellatif Bouazzaoui3, Halah Abalkhail4 and Tarek MA Owaidah4* 1Faculty of Medicine, Department of Medical Genetics, Umm Al-Qura Univers...

Amyloidosis is a rare disease defined by accumulation of extracellular amyloid systemically or within a specific organ. Localized amyloidosis of the genitourinary system is extremely rare, with the predominate location being the bladder. The imaging findings are often nonspecific and mimic urothelial carcinoma. We present a 49-year-old woman with a chief complaint of flank pain. A filling defec...

A case of facial primary nodular cutaneous amyloidosis is reported. This illustrates: the striking appearance of this unusual condition; the investigations appropriate to establish the diagnosis and to exclude underlying systemic amyloidosis or a condition which might contribute to amyloidosis; and the difficulty of successful management. Initial investigation failed to reveal any evidence of s...